Rnf6

Gene Symbol Rnf6
Entrez Gene 74132
Alt Symbol 1200013I08Rik, 5730419H05Rik, AA537053
Species Mouse
Gene Type protein-coding
Description ring finger protein (C3H2C3 type) 6
Other Description E3 ubiquitin-protein ligase RNF6|RLIM-like protein
Swissprots B2RRR0 Q8K565 Q9DBU5
Accessions EDL05800 EDL05801 EDL05802 Q9DBU5 AK004745 BAB23526 AK017576 AK029912 AK049503 AK150269 BAE29425 AK152106 BAE30953 AV586321 AY039004 AAK84435 BC138545 AAI38546 BY136428 BY323318 CX237430 XM_011241015 XP_011239317 NM_001256085 NP_001243014 NM_001256086 NP_001243015 NM_001256087 NP_001243016 NM_028774 NP_083050
Function E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator. {ECO:0000269|PubMed:11971979, ECO:0000269|PubMed:16204183}.
Subcellular Location Nucleus. Cytoplasm. Cell projection, axon. Nucleus, PML body. Note=Localizes to the PML nuclear bodies in Sertoli cells.
Tissue Specificity Widely expressed with higher expression in the testis in both germ cells and Sertoli cells. {ECO:0000269|PubMed:11971979}.

RNF6 CRISPR/Cas9 KO Plasmid (m) - sc-428743 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RNF6 HDR Plasmid (m) - sc-428743-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RNF6 Double Nickase Plasmid (m) - sc-428743-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RNF6 Double Nickase Plasmid (m2) - sc-428743-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RNF6 CRISPR Activation Plasmid (m) - sc-428743-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RNF6 CRISPR Activation Plasmid (m2) - sc-428743-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RNF6 Lentiviral Activation Particles (m) - sc-428743-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RNF6 Lentiviral Activation Particles (m2) - sc-428743-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

RNF6 siRNA (m) - sc-153053 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

RNF6 shRNA Plasmid (m) - sc-153053-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

RNF6 shRNA (m) Lentiviral Particles - sc-153053-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU018621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN40372 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40372 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

RNF6 siRNA (Mouse) - CRM9131 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

RNF6 - MBS8240475 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse RNF6 (NM_028774.3) - SHH397412 from Creative biogene

Category siRNA
Species Reactivities Mouse

RNF6 shRNA Plasmid (Mouse) - CHM9131 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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