KLHL3

Gene Symbol	KLHL3
Entrez Gene	26249
Alt Symbol	PHA2D
Species	Human
Gene Type	protein-coding
Description	kelch-like family member 3
Other Description	kelch-like protein 3
Swissprots	Q9ULU0 Q9UH75 Q9UH76 B2RBK7 Q9Y6V6 Q9UH77
Accessions	AAB97127 EAW62183 EAW62184 Q9UH77 AB032955 BAA86443 AF208068 AAF20938 AF208069 AAF20939 AF208070 AAF20995 AK300172 BAH13228 AK303916 BAH14080 AK310568 AK311594 AK314707 BAG37254 BC034035 AAH34035 BC045683 AAH45683 DA083147 NM_001257194 NP_001244123 NM_001257195 NP_001244124 NM_017415 NP_059111
Function	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation. {ECO:0000269|PubMed:14528312, ECO:0000269|PubMed:22406640, ECO:0000269|PubMed:23387299, ECO:0000269|PubMed:23453970, ECO:0000269|PubMed:23576762, ECO:0000269|PubMed:23665031}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000269|PubMed:22406640}. Cytoplasm, cytosol {ECO:0000269|PubMed:22406640}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:22406640}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KLHL3 full length protein - ab153271 from Abcam Category Protein Source Wheat germ Species Human

Human KLHL3 protein fragment - ab153272 from Abcam Category Protein Source Wheat germ Species Human

KLHL3 Antibody Blocking Peptide - LS-E4755 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLHL3 Antibody Blocking Peptide - LS-E12270 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLHL3 Antibody Blocking Peptide - LS-E14177 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KLHL3 Antibody Blocking Peptide - LS-E14176 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Kelch-Like 3 Recombinant Protein - H00026249-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Kelch-Like 3 Partial Recombinant Protein - H00026249-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

KLHL3-Antibody-Center-Blocking-Peptide - BP17126c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KLHL3 - H00026249-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

KLHL3 - H00026249-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

KLHL3 - H00026249-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

KLHL3 - H00026249-Q01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Source in vitro transl. Species Human

KLHL3 - H00026249-Q01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Source in vitro transl. Species Human

KLHL3 fusion protein - ag10843 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

KLHL3 fusion protein - Ag10580 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human Kelch-like protein 3(KLHL3) - CSB-YP890684HU CSB-EP890684HU CSB-BP890684HU CSB-MP890684HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

KLHL3 - TP318393 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Kelch-Like 3 Recombinant Protein Antigen - NBP2-14168PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

KLHL3 Peptide, Human - M34GP08287H from Creative Peptides Category Peptide Source Synthetic. Species Human

Kelch-like protein 3 (KLHL3), Recombinant Protein - MBS1429986 from MyBioSource Category Protein Prices $1,385.00, $1,385.00, $1,605.00, $1,605.00, $2,315.00, $2,315.00, $2,760.00, $2,760.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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