KPNA5

Gene Symbol	KPNA5
Entrez Gene	3841
Alt Symbol	IPOA6, SRP6
Species	Human
Gene Type	protein-coding
Description	karyopherin alpha 5 (importin alpha 6)
Other Description	importin alpha 6|importin subunit alpha-6|karyopherin subunit alpha-5
Swissprots	Q86X23 B2RAI5 O15131
Accessions	EAW48216 O15131 AA332147 AF005361 AAC51868 AK314206 BAG36882 BC047409 AAH47409 BG721781 HQ447973 ADQ32456 XM_011535805 XP_011534107 XM_011535806 XP_011534108 XM_011535807 XP_011534109 NM_002269 NP_002260
Function	Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates nuclear import of STAT1 homodimers and STAT1/STAT2 heterodimers by recognizing non- classical NLSs of STAT1 and STAT2 through ARM repeats 8-9. Recognizes influe
Subcellular Location	Cytoplasm.
Tissue Specificity	Testis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KPNA5 full length protein - ab116831 from Abcam Category Protein Source Wheat germ Species Human

Human KPNA5 full length protein - ab199581 from Abcam Category Protein Source E. coli Species Human

KPNA5 Antibody Blocking Peptide - LS-E6426 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KPNA5 Antibody Blocking Peptide - LS-E19702 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KPNA5 Antibody Blocking Peptide - LS-E31006 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KPNA5 Antibody Blocking Peptide - LS-E31220 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human KPNA5 Protein - H00003841-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

KPNA5-Antibody-N-term-Blocking-Peptide - BP19166a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

KPNA5 / Importin alpha-6 - H00003841-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

KPNA5 / Importin alpha-6 - H00003841-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

KPNA5 / Importin alpha-6 (N-term) Control Peptide - AP55609CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

KPNA5 Peptide - 6655P from ProSci Category Peptide Species Human

KPNA5 Peptide - 5989P from ProSci Category Peptide Species Human

KPNA5 fusion protein - Ag4920 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

KPNA5 fusion protein - ag4944 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human KPNA5 - KPNA5-29811TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human Importin subunit alpha-6(KPNA5) - CSB-YP012487HU CSB-EP012487HU CSB-BP012487HU CSB-MP012487HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

KPNA5 Protein - abx163849 from Abbexa Category Protein Species Human

KPNA5 Recombinant Protein Antigen - NBP2-38715PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

KPNA5 Peptide, Human - M34GP08340H from Creative Peptides Category Peptide Source Synthetic. Species Human

Importin subunit alpha-6 (KPNA5), Recombinant Protein - MBS1019504 from MyBioSource Category Protein Prices $1,330.00, $1,330.00, $1,545.00, $1,545.00, $2,195.00, $2,195.00, $2,660.00, $2,660.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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