CHIA

Gene Symbol CHIA
Entrez Gene 27159
Alt Symbol AMCASE, CHIT2, TSA1902
Species Human
Gene Type protein-coding
Description chitinase, acidic
Other Description acidic mammalian chitinase|lung-specific protein TSA1902
Swissprots Q3B866 Q5VUV4 Q32W80 Q9BZP6 Q32W79 Q5U5Z5 Q86UD8 Q9ULY3 Q9ULY4
Accessions EAW56485 EAW56486 EAW56487 EAW56488 Q9BZP6 AB025008 BAA86980 AB025009 BAA86981 AF290004 AAG60019 AK098814 AK290702 BAF83391 AY789444 AAX81431 AY789445 AAX81432 AY825504 AAX54833 AY911310 AAX81433 AY911311 AAX81434 BC036339 AAH36339 BC047336 AAH47336 BC106910 AAI06911 BC139901 AAI39902 BC139920 AAI39921 XM_006710577 XP_006710640 NM_001040623 NP_001035713 NM_001258001 NP_001244930 NM_001258002 NP_001244931 NM_001258003 NP_001244932 NM_001258004 NP_001244933 NM_001258005 NP_001244934 NM_021797 NP_068569 NM_201653 NP_970615
Function Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding. {ECO:0000269|PubMed:11085997, ECO:0000269|PubMed:18824549, ECO:0000269|PubMed:19342690, ECO:0000269|PubMed:19435888}.
Subcellular Location Isoform 3: Cytoplasm.
Tissue Specificity Detected in lung epithelial cells from asthma patients (at protein level). Highly expressed in stomach. Detected at lower levels in lung. {ECO:0000269|PubMed:11085997, ECO:0000269|PubMed:15192232}.
Top Pathways Amino sugar and nucleotide sugar metabolism

Mouse CHIA / Amcase ELISA Kit (Sandwich ELISA) - LS-F11131 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 0.156-10 ng/ml

Acidic mammalian chitinase (CHIA), Human, ELISA Kit - CSB-EL005348HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Acidic mammalian chitinase (CHIA), Human, ELISA Kit - E01A1812 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Acidic mammalian chitinase, CHIA, Human, ELISA Kit - E9061h from ARP American Research Products

Category ELISA Kit
Prices $660.00
Sizes 96 t
Range 0.156-10 ng/mL

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7234828 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7208464 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7230244 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7222576 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7202870 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7221884 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7241597 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/mL.

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7209373 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7216544 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7208893 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7205342 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Acidic mammalian chitinase (CHIA), ELISA Kit - MBS7205884 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

chitinase, acidic, ELISA Kit - MBS908954 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 7.81 mU/ml
Range 31.25 mU/ml-2000 mU/ml

Human Acidic mammalian chitinase(CHIA) ELISA kit - CSB-EL005348HU from Cusabio

Category ELISA Kit
Sensitivity 7.81 mU/ml
Range 31.25 mU/ml-2000 mU/ml

Rat CHIA / Amcase ELISA Kit (Custom ELISA) - LS-F20302 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Bovine CHIA / Amcase ELISA Kit (Custom ELISA) - LS-F20303 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Human Acidic mammalian chitinase ELISA Kit - abx251797 from Abbexa

Category ELISA Kit
Range 0.156 ng/ml - 10 ng/ml

Human CHIA / Amcase ELISA Kit (Sandwich ELISA) - LS-F13117 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 0.156-10 ng/ml

Human Acidic mammalian chitinase (CHIA) ELISA Kit - EKC32464 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 7.81 mU/ml
Range 31.25 mU/ml-2000 mU/ml

Human Acidic mammalian chitinase ELISA Kit - EKE54541 from Biomatik

Category ELISA Kit
Prices $759.00, $3,225.75, $6,072.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity The minimum detectable dose of this kit is typically less than 0.076 ng/mL
Range 0.156-10 ng/mL

CHIA - EKH4868 from Nordic BioSite

Sensitivity 0.094ng/ml
Range 0.156-10ng/ml
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