Gene Symbol | NOXA1 |
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Entrez Gene | 10811 |
Alt Symbol | NY-CO-31, SDCCAG31, p51NOX |
Species | Human |
Gene Type | protein-coding |
Description | NADPH oxidase activator 1 |
Other Description | NCF2-like protein|Nox activator 1|antigen NY-CO-31|inhibitory NADPH oxidase activator 1|p51-nox|p67phox-like factor|serologically defined colon cancer antigen 31 |
Swissprots | Q8IUS3 Q29VV0 Q29VU9 O60533 Q86UR1 Q2TAM1 |
Accessions | Q86UR1 AB095031 BAC76710 AF039697 AAC18046 AI860821 AK055812 AK098341 AY255769 AAP13480 AY927790 AAY16126 AY927791 AAY16127 BC041594 AAH41594 BC110840 AAI10841 XM_011518158 XP_011516460 XM_011518159 XP_011516461 XM_011518160 XP_011516462 NM_001256067 NP_001242996 NM_001256068 NP_001242997 NM_006647 NP_006638 |
Function | Functions as an activator of NOX1, a superoxide- producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. {ECO:0000269|PubMed:12657628, ECO:0000269|PubMed:12716910, ECO:0000269|PubMed:14617635, ECO:0000269|PubMed:14978110, ECO:0000269|PubMed:15181005, ECO:0000269|PubMed:15824103, ECO:0000269|PubMed:17602954, ECO:0000269|PubMed:19755710}. |
Subcellular Location | Cytoplasm. Cell membrane. Note=Translocation to membranes depends on NOXO1 or NCF1 and maybe RAC1. |
Tissue Specificity | Widely expressed. Detected in pancreas, liver, kidney, spleen, prostate, small intestine and colon. {ECO:0000269|PubMed:12716910}. |
NOXA1 (H-6) - sc-398873 from Santa Cruz Biotechnology
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NOXA1 (E-13) - sc-160596 from Santa Cruz Biotechnology
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Anti-NOXA1 antibody - ab68523 from Abcam
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Anti-NOXA1 antibody - ab103007 from Abcam
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Anti-NOXA1 antibody - ab172524 from Abcam
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Anti-NOXA1 Antibody (aa449-478, AP) - LS-C264582 from LifeSpan Bioscience
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Anti-NOXA1 Antibody (aa449-478, Biotin) - LS-C264584 from LifeSpan Bioscience
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Anti-NOXA1 Antibody (aa449-478, APC) - LS-C264585 from LifeSpan Bioscience
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Anti-NOXA1 Antibody (aa449-478, FITC) - LS-C264586 from LifeSpan Bioscience
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Anti-NOXA1 Antibody (aa449-478, Azide-free, HRP) - LS-C264587 from LifeSpan Bioscience
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Anti-NOXA1 Antibody (aa449-478, PE) - LS-C264588 from LifeSpan Bioscience
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Anti-NOXA1 Antibody (aa454-483) - LS-C323404 from LifeSpan Bioscience
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Anti-NOXA1 Antibody (aa176-195) - LS-C313065 from LifeSpan Bioscience
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Anti-NOXA1 Antibody (aa449-478) - LS-C162950 from LifeSpan Bioscience
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NOXA1 Antibody - NBP1-92197 from Novus Biologicals
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NOXA1 Antibody - H00010811-B01P from Novus Biologicals
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NOXA1 Antibody - H00010811-D01P from Novus Biologicals
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NOXA1 Antibody - H00010811-D01 from Novus Biologicals
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ANTI-NOXA1 (C-TERM) antibody produced in rabbit - SAB1304776 from Sigma-Aldrich
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Anti-NOXA1 antibody produced in rabbit - SAB1410129 from Sigma-Aldrich
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Anti-NOXA1 antibody produced in mouse - SAB1407057 from Sigma-Aldrich
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Anti-NOXA1 antibody produced in rabbit - HPA044781 from Sigma-Aldrich
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NOXA1 Antibody - middle region (ARP52221_P050) - ARP52221_P050 from Aviva Systems Biology
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NOXA1-Antibody-C-term - AP9567b from Abgent, a WuXi AppTec company
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NOXA1 Antibody - C-terminal region (OAAB06163) - OAAB06163 from Aviva Systems Biology
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