Gene Symbol | NOXA1 |
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Entrez Gene | 10811 |
Alt Symbol | NY-CO-31, SDCCAG31, p51NOX |
Species | Human |
Gene Type | protein-coding |
Description | NADPH oxidase activator 1 |
Other Description | NCF2-like protein|Nox activator 1|antigen NY-CO-31|inhibitory NADPH oxidase activator 1|p51-nox|p67phox-like factor|serologically defined colon cancer antigen 31 |
Swissprots | Q8IUS3 Q29VV0 Q29VU9 O60533 Q86UR1 Q2TAM1 |
Accessions | Q86UR1 AB095031 BAC76710 AF039697 AAC18046 AI860821 AK055812 AK098341 AY255769 AAP13480 AY927790 AAY16126 AY927791 AAY16127 BC041594 AAH41594 BC110840 AAI10841 XM_011518158 XP_011516460 XM_011518159 XP_011516461 XM_011518160 XP_011516462 NM_001256067 NP_001242996 NM_001256068 NP_001242997 NM_006647 NP_006638 |
Function | Functions as an activator of NOX1, a superoxide- producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. {ECO:0000269|PubMed:12657628, ECO:0000269|PubMed:12716910, ECO:0000269|PubMed:14617635, ECO:0000269|PubMed:14978110, ECO:0000269|PubMed:15181005, ECO:0000269|PubMed:15824103, ECO:0000269|PubMed:17602954, ECO:0000269|PubMed:19755710}. |
Subcellular Location | Cytoplasm. Cell membrane. Note=Translocation to membranes depends on NOXO1 or NCF1 and maybe RAC1. |
Tissue Specificity | Widely expressed. Detected in pancreas, liver, kidney, spleen, prostate, small intestine and colon. {ECO:0000269|PubMed:12716910}. |
Human NOXA1 full length protein - ab161166 from Abcam
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NOXA1 Antibody Blocking Peptide - LS-E10200 from LifeSpan Bioscience
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NOXA1 Recombinant Protein - H00010811-P01 from Novus Biologicals
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NOXA1-Antibody-C-term-Blocking-Peptide - BP9567b from Abgent, a WuXi AppTec company
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NOXA1 - H00010811-P01-10 from Acris Antibodies
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NOXA1 - H00010811-P01-25 from Acris Antibodies
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NOXA1 fusion protein - ag13410 from Proteintech Group
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NOXA1 fusion protein - Ag13411 from Proteintech Group
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Recombinant Human NADPH oxidase activator 1(NOXA1) - CSB-YP015963HU CSB-EP015963HU CSB-BP015963HU CSB-MP015963HU from Cusabio
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NOXA1 - TP308357 from Acris Antibodies
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NOXA1 Protein - NBP1-92197PEP from Novus Biologicals
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NOXA1 Peptide, Human - M34GP10528H from Creative Peptides
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NADPH oxidase activator 1 (NOXA1), Recombinant Protein - MBS1336008 from MyBioSource
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