Gene Symbol | NOXA1 |
---|---|
Entrez Gene | 10811 |
Alt Symbol | NY-CO-31, SDCCAG31, p51NOX |
Species | Human |
Gene Type | protein-coding |
Description | NADPH oxidase activator 1 |
Other Description | NCF2-like protein|Nox activator 1|antigen NY-CO-31|inhibitory NADPH oxidase activator 1|p51-nox|p67phox-like factor|serologically defined colon cancer antigen 31 |
Swissprots | Q8IUS3 Q29VV0 Q29VU9 O60533 Q86UR1 Q2TAM1 |
Accessions | Q86UR1 AB095031 BAC76710 AF039697 AAC18046 AI860821 AK055812 AK098341 AY255769 AAP13480 AY927790 AAY16126 AY927791 AAY16127 BC041594 AAH41594 BC110840 AAI10841 XM_011518158 XP_011516460 XM_011518159 XP_011516461 XM_011518160 XP_011516462 NM_001256067 NP_001242996 NM_001256068 NP_001242997 NM_006647 NP_006638 |
Function | Functions as an activator of NOX1, a superoxide- producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3. {ECO:0000269|PubMed:12657628, ECO:0000269|PubMed:12716910, ECO:0000269|PubMed:14617635, ECO:0000269|PubMed:14978110, ECO:0000269|PubMed:15181005, ECO:0000269|PubMed:15824103, ECO:0000269|PubMed:17602954, ECO:0000269|PubMed:19755710}. |
Subcellular Location | Cytoplasm. Cell membrane. Note=Translocation to membranes depends on NOXO1 or NCF1 and maybe RAC1. |
Tissue Specificity | Widely expressed. Detected in pancreas, liver, kidney, spleen, prostate, small intestine and colon. {ECO:0000269|PubMed:12716910}. |
NOXA1 CRISPR/Cas9 KO Plasmid (h) - sc-416586 from Santa Cruz Biotechnology
|
||||||||
NOXA1 HDR Plasmid (h) - sc-416586-HDR from Santa Cruz Biotechnology
|
||||||||
NOXA1 Double Nickase Plasmid (h) - sc-416586-NIC from Santa Cruz Biotechnology
|
||||||||
NOXA1 Double Nickase Plasmid (h2) - sc-416586-NIC-2 from Santa Cruz Biotechnology
|
||||||||
NOXA1 CRISPR Activation Plasmid (h) - sc-416586-ACT from Santa Cruz Biotechnology
|
||||||||
NOXA1 CRISPR Activation Plasmid (h2) - sc-416586-ACT-2 from Santa Cruz Biotechnology
|
||||||||
NOXA1 Lentiviral Activation Particles (h) - sc-416586-LAC from Santa Cruz Biotechnology
|
||||||||
NOXA1 Lentiviral Activation Particles (h2) - sc-416586-LAC-2 from Santa Cruz Biotechnology
|
||||||||
NOXA1 siRNA (h) - sc-92533 from Santa Cruz Biotechnology
|
||||||||
NOXA1 shRNA Plasmid (h) - sc-92533-SH from Santa Cruz Biotechnology
|
||||||||
NOXA1 shRNA (h) Lentiviral Particles - sc-92533-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU041231 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN15432 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15432 from Sigma-Aldrich
|
||||||||
NOXA1 siRNA (Human) - CRH7370 from Cohesion Biosciences
|
||||||||
shRNA set against Human NOXA1 (NM_006647.1) - SHH353964 from Creative biogene
|
||||||||
shRNA set against Human NOXA1(NM_006647.1) - SHR016490 from Creative biogene
|
||||||||
Human NOXA1 siRNA - orb267872 from Biorbyt
|
||||||||
NOXA1 shRNA Plasmid (Human) - CHH7370 from Cohesion Biosciences
|
||||||||
NOXA1 miRNA 3'UTR clone - MiUTR1H-06864 from Creative biogene
|