RCOR1

Gene Symbol	RCOR1
Entrez Gene	23186
Alt Symbol	COREST, RCOR
Species	Human
Gene Type	protein-coding
Description	REST corepressor 1
Other Description	-
Swissprots	Q86VG5 Q6P2I9 Q15044 Q9UKL0
Accessions	EAW81793 EAW81794 Q9UKL0 AF070627 AF155595 AAF01498 AI337324 AK026612 BC051003 AAH51003 BC064495 AAH64495 BC111590 AAI11591 D31888 BAA06686 DB455887 XM_005267453 XP_005267510 XR_943406 NM_015156 NP_055971
Function	Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation. {ECO:0000269|PubMed:11171972, ECO:0000269|PubMed:11516394, ECO:0000269|PubMed:12032298, ECO:0000269|PubMed
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:10734093, ECO:0000269|PubMed:15897453}. Note=Upon infection by HSV-1, it is partially translocated into the cytoplasm in an HSV-1-dependent manner.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:10449787}.
Top Pathways	Huntington's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rabbit anti-CoREST Antibody, Affinity Purified - PLA0043 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

REST corepressor 1, ELISA Kit - MBS9335059 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0ng/ml. Range 3.12ng/ml-100ng/ml.

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9311944 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Custom Human RCOR1/CoREST ELISA - ELH-RCOR1-1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Custom Human RCOR1 ELISA Kit - orb384728 from Biorbyt Category ELISA Kit Prices $1,411.00, $2,448.00, $5,321.00 Sizes 96 assays, 192 assays, 480 assays

Human RCOR1 ELISA Kit - E033265 from Biobool Category ELISA Kit

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9347114 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9358148 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9369786 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9369854 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9348189 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9364511 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9355363 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9350144 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9364677 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9354781 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9349222 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9350879 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9357140 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9357598 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9356567 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9369727 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9377805 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9367287 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

REST Corepressor 1 (RCOR1), ELISA Kit - MBS9363395 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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