Gene Symbol | IRX3 |
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Entrez Gene | 79191 |
Alt Symbol | IRX-1, IRXB1 |
Species | Human |
Gene Type | protein-coding |
Description | iroquois homeobox 3 |
Other Description | homeodomain protein IRXB1|iroquois homeobox protein 3|iroquois-class homeodomain protein IRX-1|iroquois-class homeodomain protein IRX-3 |
Swissprots | Q8IVC6 Q7Z4A5 P78415 Q7Z4A4 |
Accessions | AAQ16548 EAW82815 P78415 AK309146 AY335943 AAQ16549 BC023667 AAH23667 BC034328 AAH34328 DQ892008 ABM82934 EU176666 ABW03467 U90308 AAB50006 XM_005256139 XP_005256196 NM_024336 NP_077312 |
Function | Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
IRX3 (C-16) - sc-323985 from Santa Cruz Biotechnology
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IRX3 (F-8) - sc-166657 from Santa Cruz Biotechnology
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IRX3 (G-6) - sc-166877 from Santa Cruz Biotechnology
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IRX3 (M-147) - sc-30157 from Santa Cruz Biotechnology
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Anti-Iroquois homeobox protein 3 antibody - ab201097 from Abcam
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Anti-Iroquois homeobox protein 3 antibody - ab111180 from Abcam
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Anti-Iroquois homeobox protein 3 antibody - ab123341 from Abcam
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Anti-Iroquois homeobox protein 3 antibody - ab57733 from Abcam
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Anti-Iroquois homeobox protein 3 antibody [EPR12124] - ab174307 from Abcam
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Anti-Iroquois homeobox protein 3 antibody [IRX33B4C1] - ab50773 from Abcam
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Anti-IRX3 Antibody - LS-C8291 from LifeSpan Bioscience
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Anti-IRX3 Antibody - LS-C71122 from LifeSpan Bioscience
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Anti-IRX3 Antibody (clone IRX33B4C1) - LS-C184287 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa110-140, Biotin) - LS-C215274 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa110-140, AP) - LS-C215272 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa110-140, APC) - LS-C215273 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa110-140, Azide-free, HRP) - LS-C215275 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa110-140, PE) - LS-C215279 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa110-140, FITC) - LS-C215276 from LifeSpan Bioscience
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Anti-IRX3 Antibody - LS-C310781 from LifeSpan Bioscience
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Anti-IRX3 Antibody (N-Terminus) - LS-C31205 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa110-140) - LS-C322278 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa182-286) - LS-C308524 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa182-286, Azide-free) - LS-C327669 from LifeSpan Bioscience
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Anti-IRX3 Antibody (aa386-435) - LS-C30531 from LifeSpan Bioscience
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