| Gene Symbol | IRX3 |
|---|---|
| Entrez Gene | 79191 |
| Alt Symbol | IRX-1, IRXB1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | iroquois homeobox 3 |
| Other Description | homeodomain protein IRXB1|iroquois homeobox protein 3|iroquois-class homeodomain protein IRX-1|iroquois-class homeodomain protein IRX-3 |
| Swissprots | Q8IVC6 Q7Z4A5 P78415 Q7Z4A4 |
| Accessions | AAQ16548 EAW82815 P78415 AK309146 AY335943 AAQ16549 BC023667 AAH23667 BC034328 AAH34328 DQ892008 ABM82934 EU176666 ABW03467 U90308 AAB50006 XM_005256139 XP_005256196 NM_024336 NP_077312 |
| Function | Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
iroquois homeobox 3, ELISA Kit - MBS9335489 from MyBioSource
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Human IRX3 ELISA Kit - E021073 from Biobool
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anti-IRX3 antibody - ARG66166 from Arigo Biolaboratories
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