SNX33

Gene Symbol SNX33
Entrez Gene 257364
Alt Symbol SH3PX3, SH3PXD3C, SNX30
Species Human
Gene Type protein-coding
Description sorting nexin 33
Other Description SH3 and PX domain containing 3|SH3 and PX domain-containing protein 3|sorting nexin-33
Swissprots B1NM17 Q8WV41
Accessions CAL48182 CCQ43875 EAW99243 Q8WV41 AK091291 AK126563 AL833039 CAH56299 BC018775 AAH18775 DQ891695 ABM82621 DQ895211 ABM86137 EF219141 ABN09670 EF653821 ABV26009 EU831407 ACE87094 EU831499 ACE86418 NM_153271 NP_695003
Function Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes. {ECO:0000269|PubMed:18353773, ECO:0000269|PubMed:18419754, ECO:0000269|PubMed:19487689, ECO:0000269|PubMed:20964629, ECO:0000269|PubMed:21048941, ECO:0000269|PubMed:22718350}.
Subcellular Location Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic, but a minor proportion is membrane-bound (PubMed:18353773). Not associated with membranes (PubMed:21048941). {ECO:0000269|PubMed:18353773, ECO:0000269|PubMed:21048941}.
Tissue Specificity Detected in heart and pancreas. {ECO:0000269|PubMed:18353773}.

SNX33 (N-15) - sc-324326 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SNX33 (N-15): sc-324326. Western blot analysis of SNX33 expression in A431 (A) and NCI-H292 (B) whole cell lysates.

Anti-SNX33 antibody - ab101521 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SNX33 antibody (ab101521) at 1/2000 dilution + A431 whole cell lysate at 30 µg

Anti-SNX33 antibody - ab173391 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SNX33 antibody (ab173391) at 1 µg/mlLane 1 : SNX33 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Rabbit IgG at 1/7500 dilution

Anti-SNX33 antibody - ab67392 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SNX33 antibody (ab67392) at 1/500 dilutionLane 1 : SNX33 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-SNX33 antibody - C-terminal - ab198747 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling SNX33 withab198747 at 1/20 dilution.

Anti-SNX33 antibody - C-terminal - ab173615 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SNX33 antibody - C-terminal (ab173615) at 1/100 dilution + NCI-H292 cell lysate at 35 µg

Anti-SNX33 Antibody (aa389-416, AP) - LS-C269911 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX33 Antibody (aa389-416, APC) - LS-C269912 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX33 Antibody (aa389-416, Biotin) - LS-C269913 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX33 Antibody (aa389-416, FITC) - LS-C269914 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX33 Antibody (aa389-416, Azide-free, HRP) - LS-C269915 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX33 Antibody (aa388-416) - LS-C325264 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX33 Antibody (aa389-416, PE) - LS-C269916 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SNX33 Antibody (aa482-531) - LS-C186803 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human 721_B. SNX33 antibody dilution 1.0 ug/ml.

Anti-SNX33 Antibody (aa389-416) - LS-C159058 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SNX33 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The SNX33 antibody detected the SNX33 protein (arrow).

SNX33 Antibody - NBP1-81125 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: SNX33 Antibody [NBP1-81125] - Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells and islets of Langerhans.

SNX33 Antibody - NBP2-20447 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SNX33 Antibody [NBP2-20447] - Sample (30 ug of whole cell lysate) A: A431 7. 5% SDS PAGE gel, diluted at 1:2000.

SNX33 Antibody - H00257364-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SNX33 Antibody [H00257364-D01P] - Analysis of SNX33 expression in transfected 293T cell line by SNX33 polyclonal antibody.Lane 1: SH3PX3 transfected lysate(65.30 KDa).Lane 2: Non-transfected lysate.

SNX33 Antibody (3A1) - H00257364-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A1
Western Blot: SNX33 Antibody (3A1) [H00257364-M03] - Analysis of SH3PX3 expression in transfected 293T cell line by SH3PX3 monoclonal antibody (M03), clone 3A1. Lane 1: SH3PX3 transfected lysatE (65.265 KDa). Lane 2: Non-transfected lysate.

SNX33 Antibody - H00257364-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SNX33 Antibody [H00257364-A01] - SH3PX3 polyclonal antibody (A01), Lot # 060623JCS1 Western Blot analysis of SH3PX3 expression in Jurkat ( Cat # L017V1 ).

SNX33 Antibody - H00257364-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SNX33 Antibody [H00257364-B01P] - Analysis of SNX33 expression in transfected 293T cell line by SNX33 polyclonal antibody.  Lane 1: SH3PX3 transfected lysate(63.14 KDa). Lane 2: Non-transfected lysate.

SNX33 Antibody - H00257364-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SNX33 Antibody [H00257364-B01] - analysis of SH3PX3 expression in transfected 293T cell line by SH3PX3 MaxPab polyclonal antibody (B01). Lane 1: SH3PX3 transfected lysate (65.30 KDa). Lane 2: Non-transfected lysate.

SNX33 Antibody - H00257364-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-SH3PX3 antibody produced in mouse - SAB1400851 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A1
<B>Immunoblotting</B><BR/>Monoclonal Anti-SH3PX3, antibody produced in mouse, clone 3A1, purified immunoglobulin: <B>Cat. No. SAB1400851</B>: Antibody concentration: 1.0 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.

Anti-SH3PX3 antibody produced in rabbit - SAB1410472 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SH3PX3: <B>Cat. No. SAB1410472</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~65.3 kDa using SNX33 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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