SNX33

Gene Symbol	SNX33
Entrez Gene	257364
Alt Symbol	SH3PX3, SH3PXD3C, SNX30
Species	Human
Gene Type	protein-coding
Description	sorting nexin 33
Other Description	SH3 and PX domain containing 3|SH3 and PX domain-containing protein 3|sorting nexin-33
Swissprots	B1NM17 Q8WV41
Accessions	CAL48182 CCQ43875 EAW99243 Q8WV41 AK091291 AK126563 AL833039 CAH56299 BC018775 AAH18775 DQ891695 ABM82621 DQ895211 ABM86137 EF219141 ABN09670 EF653821 ABV26009 EU831407 ACE87094 EU831499 ACE86418 NM_153271 NP_695003
Function	Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes. {ECO:0000269|PubMed:18353773, ECO:0000269|PubMed:18419754, ECO:0000269|PubMed:19487689, ECO:0000269|PubMed:20964629, ECO:0000269|PubMed:21048941, ECO:0000269|PubMed:22718350}.
Subcellular Location	Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic, but a minor proportion is membrane-bound (PubMed:18353773). Not associated with membranes (PubMed:21048941). {ECO:0000269|PubMed:18353773, ECO:0000269|PubMed:21048941}.
Tissue Specificity	Detected in heart and pancreas. {ECO:0000269|PubMed:18353773}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SH3PX3 293T Cell Transient Overexpression Lysate(Denatured) - H00257364-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

SNX33 overexpression lysate - LY407121 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

SNX33 293 Cell Lysate - 404126 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

SNX33 Overexpression Lysate (Denatured) - H00257364-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

SNX33 Overexpression Lysate (Native) - NBL1-16316 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

SNX33 Over-expression Lysate Product - GWB-6B5ED0 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

SNX33 Overexpression Lysate (Denatured) - H00257364-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human SNX33 Knockdown Stable Cell Line - CSC-DC014864 from Creative biogene Category Cell Line Species Human

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