SNX33

Gene Symbol SNX33
Entrez Gene 257364
Alt Symbol SH3PX3, SH3PXD3C, SNX30
Species Human
Gene Type protein-coding
Description sorting nexin 33
Other Description SH3 and PX domain containing 3|SH3 and PX domain-containing protein 3|sorting nexin-33
Swissprots B1NM17 Q8WV41
Accessions CAL48182 CCQ43875 EAW99243 Q8WV41 AK091291 AK126563 AL833039 CAH56299 BC018775 AAH18775 DQ891695 ABM82621 DQ895211 ABM86137 EF219141 ABN09670 EF653821 ABV26009 EU831407 ACE87094 EU831499 ACE86418 NM_153271 NP_695003
Function Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking via its interactions with membranes, WASL, DNM1 and DNM2. Acts both during interphase and at the end of mitotic cell divisions. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides. Promotes membrane tubulation (in vitro). May promote the formation of macropinosomes. {ECO:0000269|PubMed:18353773, ECO:0000269|PubMed:18419754, ECO:0000269|PubMed:19487689, ECO:0000269|PubMed:20964629, ECO:0000269|PubMed:21048941, ECO:0000269|PubMed:22718350}.
Subcellular Location Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic, but a minor proportion is membrane-bound (PubMed:18353773). Not associated with membranes (PubMed:21048941). {ECO:0000269|PubMed:18353773, ECO:0000269|PubMed:21048941}.
Tissue Specificity Detected in heart and pancreas. {ECO:0000269|PubMed:18353773}.

Human SNX33 full length protein - ab166081 from Abcam

Category Protein
Source Wheat germ
Species Human
ab166081 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human SNX33 protein fragment - ab166082 from Abcam

Category Protein
Source Wheat germ
Species Human
ab166082 on a 12.5% SDS-PAGE stained with Coomassie Blue.

SNX33 Antibody Blocking Peptide - LS-E5177 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SNX33 Antibody Blocking Peptide - LS-E24138 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SNX33 Recombinant Protein - H00257364-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human SNX33 Protein - H00257364-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human
Western Blot: SNX33 Partial Recombinant Protein [h00257364-Q01]

SNX33-Antibody-C-term-Blocking-Peptide - BP17608b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Sorting nexin-33 (SNX33) - H00257364-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Sorting nexin-33 (SNX33) - H00257364-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

Sorting nexin-33 (SNX33) - H00257364-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Sorting nexin-33 (SNX33) - H00257364-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SNX33 fusion protein - ag9752 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

SNX33 fusion protein - Ag9915 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

Recombinant Human Sorting nexin-33(SNX33) - CSB-YP851969HU CSB-EP851969HU CSB-BP851969HU CSB-MP851969HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Sorting nexin-33 (SNX33) - TP305879 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
Sorting nexin-33 (SNX33)

SNX33 Recombinant Protein Antigen - NBP1-81125PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

SNX33 Peptide, Human - M34GP14864H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Sorting nexin-33 (SNX33), Recombinant Protein - MBS1434467 from MyBioSource

Category Protein
Prices $1,370.00, $1,370.00, $1,590.00, $1,590.00, $2,285.00, $2,285.00, $2,750.00, $2,750.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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