Gene Symbol | DOLPP1 |
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Entrez Gene | 57171 |
Alt Symbol | LSFR2 |
Species | Human |
Gene Type | protein-coding |
Description | dolichyldiphosphatase 1 |
Other Description | dolichyl pyrophosphate phosphatase 1|linked to Surfeit genes in Fugu rubripes 2 |
Swissprots | A8K3U8 B0QZG4 Q86YN1 Q9Y3G1 Q96GF8 |
Accessions | CAB44348 CAB44349 EAW87867 EAW87868 EAW87869 EAW87870 EAW87871 EAW87872 Q86YN1 AK290713 BAF83402 AK293627 BAG57084 AY189675 AAO34712 BC009493 AAH09493 BC022553 BC033686 AAH33686 BC040152 AAH40152 BC067858 DA590931 DQ655991 NM_001135917 NP_001129389 NM_020438 NP_065171 NR_072983 |
Function | Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity). {ECO:0000250|UniProtKB:Q9JMF7}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | N-Glycan biosynthesis |
Human DOLPP1 full length protein - ab163511 from Abcam
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DOLPP1 Antibody Blocking Peptide - LS-E2595 from LifeSpan Bioscience
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DOLPP1 Antibody Blocking Peptide - LS-E17874 from LifeSpan Bioscience
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Recombinant Human DOLPP1 Protein - H00057171-P01 from Novus Biologicals
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DOLPP1-Antibody-C-term-Blocking-peptide - BP13656b from Abgent, a WuXi AppTec company
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DOLPP1 Blocking Peptide - 33R-1013 from Fitzgerald
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Dolichyldiphosphatase 1 - H00057171-P01-10 from Acris Antibodies
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Dolichyldiphosphatase 1 - H00057171-P01-25 from Acris Antibodies
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DOLPP1 fusion protein - ag11723 from Proteintech Group
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DOLPP1 Recombinant Protein Antigen - NBP1-81286PEP from Novus Biologicals
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DOLPP1 Peptide, Human - M34GP04491H from Creative Peptides
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Dolichyldiphosphatase 1 (DOLPP1), Recombinant Protein - MBS1176325 from MyBioSource
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Dolichyldiphosphatase 1 (DOLPP1), Recombinant Protein - MBS1223707 from MyBioSource
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Dolichyldiphosphatase 1 (DOLPP1), Recombinant Protein - MBS1062188 from MyBioSource
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Dolichyldiphosphatase 1 (DOLPP1), Recombinant Protein - MBS7013834 from MyBioSource
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Dolichyldiphosphatase 1 (DOLPP1), Recombinant Protein - MBS7013836 from MyBioSource
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Dolichyldiphosphatase 1 (DOLPP1), Recombinant Protein - MBS7013838 from MyBioSource
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Dolichyldiphosphatase 1 (DOLPP1), Recombinant Protein - MBS7013839 from MyBioSource
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