Gene Symbol | DOLPP1 |
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Entrez Gene | 57171 |
Alt Symbol | LSFR2 |
Species | Human |
Gene Type | protein-coding |
Description | dolichyldiphosphatase 1 |
Other Description | dolichyl pyrophosphate phosphatase 1|linked to Surfeit genes in Fugu rubripes 2 |
Swissprots | A8K3U8 B0QZG4 Q86YN1 Q9Y3G1 Q96GF8 |
Accessions | CAB44348 CAB44349 EAW87867 EAW87868 EAW87869 EAW87870 EAW87871 EAW87872 Q86YN1 AK290713 BAF83402 AK293627 BAG57084 AY189675 AAO34712 BC009493 AAH09493 BC022553 BC033686 AAH33686 BC040152 AAH40152 BC067858 DA590931 DQ655991 NM_001135917 NP_001129389 NM_020438 NP_065171 NR_072983 |
Function | Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity). {ECO:0000250|UniProtKB:Q9JMF7}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | N-Glycan biosynthesis |
DOLPP1 (N-13) - sc-138918 from Santa Cruz Biotechnology
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DOLPP1 (T-13) - sc-138919 from Santa Cruz Biotechnology
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Anti-DOLPP1 antibody - ab116398 from Abcam
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Anti-DOLPP1 antibody - ab81172 from Abcam
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Anti-DOLPP1 Antibody (aa207-236, PE) - LS-C256248 from LifeSpan Bioscience
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Anti-DOLPP1 Antibody (aa207-236, AP) - LS-C259207 from LifeSpan Bioscience
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Anti-DOLPP1 Antibody (aa207-236, APC) - LS-C259208 from LifeSpan Bioscience
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Anti-DOLPP1 Antibody (aa207-236, FITC) - LS-C259210 from LifeSpan Bioscience
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Anti-DOLPP1 Antibody (aa207-236, Biotin) - LS-C259209 from LifeSpan Bioscience
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Anti-DOLPP1 Antibody (aa206-236) - LS-C320930 from LifeSpan Bioscience
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Anti-DOLPP1 Antibody (aa207-236, Azide-free, HRP) - LS-C259211 from LifeSpan Bioscience
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Anti-DOLPP1 Antibody (N-Terminus) - LS-C81394 from LifeSpan Bioscience
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Anti-DOLPP1 Antibody (aa207-236) - LS-C167505 from LifeSpan Bioscience
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DOLPP1 Antibody - NBP1-59981 from Novus Biologicals
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DOLPP1 Antibody - NBP1-81286 from Novus Biologicals
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Anti-DOLPP1 antibody produced in rabbit - HPA019179 from Sigma-Aldrich
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Anti-DOLPP1 antibody produced in rabbit - AV49511 from Sigma-Aldrich
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DOLPP1 antibody - N-terminal region (ARP49511_P050) - ARP49511_P050 from Aviva Systems Biology
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DOLPP1-Antibody-C-term - AP13656b from Abgent, a WuXi AppTec company
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DOLPP1 antibody, N-term - GTX46054 from GeneTex
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DOLPP1 Antibody - C-terminal region (OAAB09956) - OAAB09956 from Aviva Systems Biology
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DOLPP1 antibody - 70R-6895 from Fitzgerald
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DOLPP1 Antibody - 26-412 from ProSci
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DOLPP1 Antibody - GWB-MR534C from Genway Biotech
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Anti-DOLPP1 monoclonal antibody - DCABH-15211 from Creative Diagnostics
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