Gene Symbol | NLRP5 |
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Entrez Gene | 126206 |
Alt Symbol | CLR19.8, MATER, NALP5, PAN11, PYPAF8 |
Species | Human |
Gene Type | protein-coding |
Description | NLR family, pyrin domain containing 5 |
Other Description | NACHT, LRR and PYD domains-containing protein 5|NACHT, leucine rich repeat and PYD containing 5|mater protein homolog|maternal antigen that embryos require|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5 |
Swissprots | Q86W29 P59047 A8MTY4 |
Accessions | P59047 AY054986 AAL15549 AY154460 AAO18156 BC141431 AAI41432 XM_011526444 XP_011524746 NM_153447 NP_703148 |
Function | As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. {ECO:0000250}. |
Subcellular Location | Mitochondrion {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions (By similarity). {ECO:0000250}. |
Tissue Specificity | Oocyte-specific. |
NLRP5 / NALP5 Antibody Blocking Peptide - LS-E30991 from LifeSpan Bioscience
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NLRP5 Blocking Peptide - NBP1-76289PEP from Novus Biologicals
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NLRP5-Antibody-C-term-Blocking-peptide - BP13418b from Abgent, a WuXi AppTec company
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NALP5 Peptide - GTX85158-PEP from GeneTex
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NLRP5 Blocking Peptide - 33R-4810 from Fitzgerald
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NLRP5 control peptide - AP26262CP-N from Acris Antibodies
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NALP5 Peptide - 5959P from ProSci
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Recombinant Human NACHT, LRR and PYD domains-containing protein 5(NLRP5) ,partia - CSB-YP015873HU CSB-EP015873HU CSB-BP015873HU CSB-MP015873HU from Cusabio
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NLRP5 Recombinant Protein Antigen - NBP2-49219PEP from Novus Biologicals
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NLRP5 Peptide, Human - M34GP10441H from Creative Peptides
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NACHT, LRR and PYD domains-containing protein 5 (NLRP5), partial, Recombinant Protein - MBS956762 from MyBioSource
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