Gene Symbol | HCRTR1 |
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Entrez Gene | 3061 |
Alt Symbol | OX1R |
Species | Human |
Gene Type | protein-coding |
Description | hypocretin (orexin) receptor 1 |
Other Description | hypocretin receptor 1|hypocretin receptor type 1|hypocretin receptor-1|orexin receptor 1|orexin receptor type 1|orexin receptor-1|ox-1-R|ox1-R |
Swissprots | O43613 A8K3A6 Q9HBV6 |
Accessions | AAG28020 AAL47214 AAL50221 CAC34687 EAX07600 EAX07601 EAX07602 O43613 AF041243 AAC39601 AK290521 BAF83210 BC035686 BC074796 AAH74796 CO960455 DA803650 XM_011541308 XP_011539610 NM_001525 NP_001516 |
Function | Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
Human Orexin Receptor 1 full length protein - ab158648 from Abcam
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Orexin Receptor 1 peptide - ab188501 from Abcam
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OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E3920 from LifeSpan Bioscience
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OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E23781 from LifeSpan Bioscience
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OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E23780 from LifeSpan Bioscience
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OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E26744 from LifeSpan Bioscience
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OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E29158 from LifeSpan Bioscience
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OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E29159 from LifeSpan Bioscience
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OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E29167 from LifeSpan Bioscience
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Recombinant Human Orexin R1/HCRTR1 Protein - H00003061-P01 from Novus Biologicals
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Recombinant Human Orexin R1/HCRTR1 Protein - H00003061-G01 from Novus Biologicals
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HCRTR1-Antibody-Center-Blocking-Peptide - BP16116c from Abgent, a WuXi AppTec company
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OX1R and OX2R blocking peptide - GTX88715-PEP from GeneTex
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HCRTR1 Immunizing peptide - orb17960 from Biorbyt
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Orexin Receptor 1 and 2 Peptide - AC21-1580-P from Abcore
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Orexin Receptor 1 Peptide - AC21-0749-P from Abcore
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Orexin receptor type 1 - H00003061-G01 from Acris Antibodies
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Orexin receptor type 1 - H00003061-P01 from Acris Antibodies
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Orexin receptor type 1 - H00003061-P01-10 from Acris Antibodies
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Orexin receptor type 1 - H00003061-P01-25 from Acris Antibodies
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Orexin Receptor 1 Peptide - 45-069P from ProSci
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OX1 Receptor Peptide - 46-119P from ProSci
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HCRTR1 fusion protein - ag12269 from Proteintech Group
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HCRTR1 fusion protein - ag12263 from Proteintech Group
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Orexin receptor 1, Peptide - MBS428156 from MyBioSource
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