HCRTR1

Gene Symbol HCRTR1
Entrez Gene 3061
Alt Symbol OX1R
Species Human
Gene Type protein-coding
Description hypocretin (orexin) receptor 1
Other Description hypocretin receptor 1|hypocretin receptor type 1|hypocretin receptor-1|orexin receptor 1|orexin receptor type 1|orexin receptor-1|ox-1-R|ox1-R
Swissprots O43613 A8K3A6 Q9HBV6
Accessions AAG28020 AAL47214 AAL50221 CAC34687 EAX07600 EAX07601 EAX07602 O43613 AF041243 AAC39601 AK290521 BAF83210 BC035686 BC074796 AAH74796 CO960455 DA803650 XM_011541308 XP_011539610 NM_001525 NP_001516
Function Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Top Pathways Neuroactive ligand-receptor interaction

Human Orexin Receptor 1 full length protein - ab158648 from Abcam

Category Protein
Source Wheat germ
Species Human
ab158648 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Orexin Receptor 1 peptide - ab188501 from Abcam

Category Peptide

OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E3920 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E23781 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E23780 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E26744 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E29158 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E29159 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

OX1R / Orexin Receptor 1 Antibody Blocking Peptide - LS-E29167 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Recombinant Human Orexin R1/HCRTR1 Protein - H00003061-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

Recombinant Human Orexin R1/HCRTR1 Protein - H00003061-G01 from Novus Biologicals

Category Protein
Prices $569.00
Sizes 10 µg
Source Wheat Germ
Species Human

HCRTR1-Antibody-Center-Blocking-Peptide - BP16116c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

OX1R and OX2R blocking peptide - GTX88715-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Dog, Pig, Rat, Bovine

HCRTR1 Immunizing peptide - orb17960 from Biorbyt

Category Peptide
Prices $247.00
Sizes 100 μg
Species Human, Mouse, Rat

Orexin Receptor 1 and 2 Peptide - AC21-1580-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

Orexin Receptor 1 Peptide - AC21-0749-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

Orexin receptor type 1 - H00003061-G01 from Acris Antibodies

Category Protein
Prices $550.00
Sizes 10 µg
Species Human

Orexin receptor type 1 - H00003061-P01 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 2 µg
Species Human

Orexin receptor type 1 - H00003061-P01-10 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

Orexin receptor type 1 - H00003061-P01-25 from Acris Antibodies

Category Protein
Prices $520.00
Sizes 25 µg
Species Human

Orexin Receptor 1 Peptide - 45-069P from ProSci

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human

OX1 Receptor Peptide - 46-119P from ProSci

Category Peptide
Species Human, Mouse, Rat

HCRTR1 fusion protein - ag12269 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

HCRTR1 fusion protein - ag12263 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Orexin receptor 1, Peptide - MBS428156 from MyBioSource

Category Peptide
Prices $175.00
Sizes 100 µg
Species Human, Mouse, Rat, Dog, Sheep
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