Gene Symbol | JUN |
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Entrez Gene | 3725 |
Alt Symbol | AP-1, AP1, c-Jun |
Species | Human |
Gene Type | protein-coding |
Description | jun proto-oncogene |
Other Description | Jun activation domain binding protein|activator protein 1|enhancer-binding protein AP1|jun oncogene|p39|proto-oncogene c-Jun|transcription factor AP-1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog |
Swissprots | Q6FHM7 Q96G93 P05412 |
Accessions | AAA59197 AAO22993 CAM91157 EAX06628 P05412 BC002646 BC006175 AAH06175 BC009874 AAH09874 BC068522 AAH68522 BG831943 BI793062 BT019759 AAV38564 BU782554 CD370800 CR541724 CAG46525 CR541752 CAG46552 DQ896432 ABM87431 NM_002228 NP_002219 |
Function | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. {ECO:0000269|PubMed:10995748, ECO:0000269|PubMed:17210646}. |
Subcellular Location | Nucleus. |
Top Pathways | TNF signaling pathway, Estrogen signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, Inflammatory bowel disease (IBD) |
PathScan® Phospho-c-Jun (Ser63) Sandwich ELISA Kit II - 7145 from Cell Signaling Technology
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PathScan ® Phospho-c-Jun (Ser63) Chemiluminescent Sandwich ELISA Kit - 7027 from Cell Signaling Technology
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PathScan ® Phospho-c-Jun (Ser63) Sandwich ELISA Antibody Pair - 7141 from Cell Signaling Technology
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PathScan® Total c-Jun Sandwich ELISA Kit II - 7150 from Cell Signaling Technology
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PathScan ® Total c-Jun Sandwich ELISA Antibody Pair - 7314 from Cell Signaling Technology
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PathScan ® Total c-Jun Chemiluminescent Sandwich ELISA Kit - 7028 from Cell Signaling Technology
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PathScan® Phospho-c-Jun (Ser63) Sandwich ELISA Kit - 7260 from Cell Signaling Technology
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PathScan® Total c-Jun Sandwich ELISA Kit - 7270 from Cell Signaling Technology
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c-Jun (pS73) PhosphoTracer ELISA Kit - ab119621 from Abcam
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c-Jun pSer73 + Total PhosphoTracer ELISA Kit - ab119657 from Abcam
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c-Jun Total PhosphoTracer ELISA Kit - ab119622 from Abcam
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Mouse/Human/Rat JUN / c-Jun ELISA Kit (DNA-Binding ELISA) - LS-F732 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Ser63) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1475 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Ser73) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1476 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Thr231) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1764 from LifeSpan Bioscience
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Mouse/Human/Rat JUN / c-Jun ELISA Kit (Cell-Based ELISA) - LS-F1884 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Thr239) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F850 from LifeSpan Bioscience
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Human/Rat Phospho-JUN / c-Jun (Thr91) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F851 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Thr93) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F852 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Ser63) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F847 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Ser249) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F846 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Ser243) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F849 from LifeSpan Bioscience
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Human Phospho-JUN / c-Jun (Ser73) ELISA Kit (DNA-Binding Phosphorylation ELISA) - LS-F848 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Tyr170) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1550 from LifeSpan Bioscience
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Mouse/Human/Rat Phospho-JUN / c-Jun (Ser243) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1546 from LifeSpan Bioscience
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