Gene Symbol | JUN |
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Entrez Gene | 3725 |
Alt Symbol | AP-1, AP1, c-Jun |
Species | Human |
Gene Type | protein-coding |
Description | jun proto-oncogene |
Other Description | Jun activation domain binding protein|activator protein 1|enhancer-binding protein AP1|jun oncogene|p39|proto-oncogene c-Jun|transcription factor AP-1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog |
Swissprots | Q6FHM7 Q96G93 P05412 |
Accessions | AAA59197 AAO22993 CAM91157 EAX06628 P05412 BC002646 BC006175 AAH06175 BC009874 AAH09874 BC068522 AAH68522 BG831943 BI793062 BT019759 AAV38564 BU782554 CD370800 CR541724 CAG46525 CR541752 CAG46552 DQ896432 ABM87431 NM_002228 NP_002219 |
Function | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. {ECO:0000269|PubMed:10995748, ECO:0000269|PubMed:17210646}. |
Subcellular Location | Nucleus. |
Top Pathways | TNF signaling pathway, Estrogen signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, Inflammatory bowel disease (IBD) |
c-Jun peptide - ab7998 from Abcam
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Human c-Jun full length protein - ab54318 from Abcam
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Human c-Jun full length protein - ab84134 from Abcam
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Human c-Jun full length protein - ab54319 from Abcam
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Human c-Jun protein fragment - ab43600 from Abcam
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Human c-Jun protein fragment - ab125782 from Abcam
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Rat c-Jun protein fragment - ab58904 from Abcam
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JUN / c-Jun Antibody Blocking Peptide - LS-E10771 from LifeSpan Bioscience
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JUN / c-Jun Antibody Blocking Peptide - LS-E10772 from LifeSpan Bioscience
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JUN / c-Jun Antibody Blocking Peptide - LS-E10911 from LifeSpan Bioscience
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JUN / c-Jun Antibody Blocking Peptide - LS-E7519 from LifeSpan Bioscience
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JUN / c-Jun Blocking Peptide - LS-E7336 from LifeSpan Bioscience
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JUN / c-Jun Antibody Blocking Peptide - LS-E7267 from LifeSpan Bioscience
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JUN / c-Jun Antibody Blocking Peptide - LS-E7266 from LifeSpan Bioscience
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JUN / c-Jun Antibody Blocking Peptide - LS-E13684 from LifeSpan Bioscience
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JUN / c-Jun Antibody Blocking Peptide - LS-E13685 from LifeSpan Bioscience
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Recombinant Human Jun Protein - NBP1-99207 from Novus Biologicals
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c-jun Recombinant Protein - H00003725-P01 from Novus Biologicals
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c-jun Partial Recombinant Protein - H00003725-Q01 from Novus Biologicals
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Recombinant Human Jun Protein - P4181 from Novus Biologicals
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Recombinant Human c-jun Protein - NBP1-72285 from Novus Biologicals
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Jun Peptide - P0782 from Novus Biologicals
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Jun Peptide - P0780 from Novus Biologicals
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Jun Peptide - P0779 from Novus Biologicals
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Jun Peptide - P0777 from Novus Biologicals
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