Gene Symbol | JUN |
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Entrez Gene | 3725 |
Alt Symbol | AP-1, AP1, c-Jun |
Species | Human |
Gene Type | protein-coding |
Description | jun proto-oncogene |
Other Description | Jun activation domain binding protein|activator protein 1|enhancer-binding protein AP1|jun oncogene|p39|proto-oncogene c-Jun|transcription factor AP-1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog |
Swissprots | Q6FHM7 Q96G93 P05412 |
Accessions | AAA59197 AAO22993 CAM91157 EAX06628 P05412 BC002646 BC006175 AAH06175 BC009874 AAH09874 BC068522 AAH68522 BG831943 BI793062 BT019759 AAV38564 BU782554 CD370800 CR541724 CAG46525 CR541752 CAG46552 DQ896432 ABM87431 NM_002228 NP_002219 |
Function | Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. {ECO:0000269|PubMed:10995748, ECO:0000269|PubMed:17210646}. |
Subcellular Location | Nucleus. |
Top Pathways | TNF signaling pathway, Estrogen signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, Inflammatory bowel disease (IBD) |
JUN 293T Cell Transient Overexpression Lysate(Denatured) - H00003725-T01 from Acris Antibodies
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JUN overexpression lysate - LY400825 from Acris Antibodies
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JUN 293 Cell Lysate - 400787 from ABBIOTEC
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c-jun Overexpression Lysate (Denatured) - H00003725-T01 from Novus Biologicals
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c-jun Overexpression Lysate (Native) - NBL1-12116 from Novus Biologicals
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c-Jun (h): 293 Lysate - sc-110759 from Santa Cruz Biotechnology
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c-Jun (h): 293T Lysate - sc-159456 from Santa Cruz Biotechnology
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c-Jun (h): CHO Lysate - sc-110019 from Santa Cruz Biotechnology
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JUN Over-expression Lysate Product - GWB-25E290 from Genway Biotech
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Panoply™ Human JUN Knockdown Stable Cell Line - CSC-DC007878 from Creative biogene
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Human JUN Knockout Cell Line-HeLa - CSC-RT1327 from Creative biogene
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JUN KO Cell Lysate-HeLa - CLKO-1179 from Creative biogene
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