RAC3

Gene Symbol	RAC3
Entrez Gene	5881
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Other Description	p21-Rac3\|ras-related C3 botulinum toxin substrate 3\|rho family, small GTP binding protein Rac3
Swissprots	Q5U0M8 P60763
Accessions	P60763 AF008591 AAC51667 AF498966 AAM21113 BC009605 AAH09605 BC015197 AAH15197 BT019443 AAV38250 BU731383 DQ893123 ABM84049 DQ896400 ABM87399 XM_005256390 XP_005256447 NM_005052 NP_005043
Function	Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner. {ECO:0000269\|PubMed:11756406, ECO:0000269\|PubMed:11956649}.
Subcellular Location	Cytoplasm. Endomembrane system. Cell projection, lamellipodium. Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton. Note=Membrane-associated when activated. Colocalizes with NRBP to endomembranes and at the cell periphery in lamellipodia. Colocalized with CIB1 in the perinuclear area and at the cell periphery.
Tissue Specificity	Highest levels in brain, also detected in heart, placenta and pancreas.
Top Pathways	Sphingolipid signaling pathway, cAMP signaling pathway, Choline metabolism in cancer, Rap1 signaling pathway, Wnt signaling pathway

Anti-RAC3 antibody - ab105065 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RAC3 antibody [7A6C12] - C-terminal - ab170138 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	7A6C12

All lanes : Anti-RAC3 antibody [7A6C12] - C-terminal (ab170138) at 1/100 dilutionLane 1 : Recombinant RAC1 protein (His tagged)Lane 2 : Recombinant RAC2 protein (His tagged)Lane 3 : Recombinant RAC3 protein (His tagged)

Anti-RAC3 antibody [EPR6679(B)] - ab124943 from Abcam

Prices	$313.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6679(B)

All lanes : Anti-RAC3 antibody [EPR6679(B)] (ab124943) at 1/1000 dilutionLane 1 : Human fetal brain lysate Lane 2 : SH-SY5Y cell lysateLane 3 : JAR cell lysate Lane 4 : BxPC-3 cell lysateLysates/proteins at 10 µg per lane.Secondarystandard HRP labelled goat anti-rabbit at 1/2000 dilutiondeveloped using the ECL technique

Anti-RAC3 antibody [EPR6680] - ab129062 from Abcam

Prices	$313.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6680

All lanes : Anti-RAC3 antibody [EPR6680] (ab129062) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : Fetal brain lysateLane 3 : SH-SY5Y cell lysateLane 4 : JAR cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-RAC3 Antibody (aa1-192) - LS-C311670 from LifeSpan Bioscience

Prices	$250.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-RAC3 Antibody (Internal, clone EPR6680) - LS-C152480 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR6680

IHC of paraffin-embedded human breast carcinoma tissue using anti-RAC3 antibody.

RAC3 Antibody - NBP2-32058 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: RAC3 Antibody [NBP2-32058] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4

RAC3 Antibody - H00005881-D01P from Novus Biologicals

Prices	$399.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-RAC3 antibody produced in rabbit - HPA047820 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-RAC3: <B>Cat. No. HPA047820</B>: Immunohistochemical staining of Human bone marrow shows distinct cytoplasmic positivity in hematopoietic cells.

Anti-RAC3 antibody produced in rabbit - SAB1401325 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Polyclonal Anti-RAC3, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401325</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~21.40 kDa using RAC3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

RAC3 antibody - 70R-19740 from Fitzgerald

Prices	$375.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

RAC3 Polyclonal Antibody - A4067 from ABclonal

Prices	$200.00, $480.00
Sizes	50 µg, 200 µg
Host	Rabbit
Clonality	Polyclonal

RAC3 Polyclonal Antibody - A7498 from ABclonal

Prices	$130.00, $220.00, $380.00
Sizes	50 µl, 100 µl, 200 µl
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts of various cell lines, using RAC3 antibody.

RAC3 Antibody - abx002989 from Abbexa

Host	Rabbit
Clonality	Polyclonal

RAC3 antibody - 16117-1-AP from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical of paraffin-embedded human brain using 16117-1-AP(RAC1/2/3 antibody) at dilution of 1:100 (under 10x lens)

RAC3 antibody - H00005881-D01P from Acris Antibodies

Prices	$390.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot analysis of RAC3 expression in transfected 293T cell line (H00005881-T03) by RAC3 MaxPab polyclonal antibody. Lane 1: RAC3 transfected lysate(21.40 KDa). Lane 2: Non-transfected lysate.

Anti-RAC3, Polyclonal Antibody - 25-A4067 from ARP American Research Products

Prices	$299.00, $449.00
Sizes	100 µg, 200 µg
Host	Rabbit
Clonality	Polyclonal

Anti-RAC3 antibody - STJ29634 from St John's Laboratory Ltd

Host	Rabbit
Clonality	Polyclonal

RAC3 antibody - STJ25275 from St John's Laboratory Ltd

Host	Rabbit
Clonality	Polyclonal

RAC1/2/3 antibody - 16117-1-AP from Proteintech Group

Prices	$279.00
Sizes	con: 45 μg/150μl
Host	Rabbit
Clonality	Polyclonal

human brain tissue were subjected to SDS PAGE followed by western blot with 16117-1-AP(RAC1/2/3 antibody) at dilution of 1:1000

RAC3-Specific antibody - 24073-1-AP from Proteintech Group

Host	Rabbit
Clonality	Polyclonal

RAC3 - A4067 from NeoScientific

Prices	$480.00
Sizes	200 µg
Host	Rabbit
Clonality	Polyclonal

RAC3 Polyclonal Antibody - EAP2446 from Elabscience

Prices	$296.00, $485.00
Sizes	120 μl, 200 μl
Host	Rabbit
Clonality	Polyclonal

Anti-RAC3 monoclonal antibody - DCABH-13162 from Creative Diagnostics

Host	Rabbit
Clonality	Monoclonal

Anti-RAC3 monoclonal antibody, clone 8B7D23 - DCABH-5360 from Creative Diagnostics

Host	Mouse
Clonality	Monoclonal
Clone	8B7D23

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