RAC3

Gene Symbol	RAC3
Entrez Gene	5881
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Other Description	p21-Rac3|ras-related C3 botulinum toxin substrate 3|rho family, small GTP binding protein Rac3
Swissprots	Q5U0M8 P60763
Accessions	P60763 AF008591 AAC51667 AF498966 AAM21113 BC009605 AAH09605 BC015197 AAH15197 BT019443 AAV38250 BU731383 DQ893123 ABM84049 DQ896400 ABM87399 XM_005256390 XP_005256447 NM_005052 NP_005043
Function	Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner. {ECO:0000269|PubMed:11756406, ECO:0000269|PubMed:11956649}.
Subcellular Location	Cytoplasm. Endomembrane system. Cell projection, lamellipodium. Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton. Note=Membrane-associated when activated. Colocalizes with NRBP to endomembranes and at the cell periphery in lamellipodia. Colocalized with CIB1 in the perinuclear area and at the cell periphery.
Tissue Specificity	Highest levels in brain, also detected in heart, placenta and pancreas.
Top Pathways	Sphingolipid signaling pathway, cAMP signaling pathway, Choline metabolism in cancer, Rap1 signaling pathway, Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RAC3 full length protein - ab89816 from Abcam Category Protein Source E. coli Species Human

Human RAC3 full length protein - ab103470 from Abcam Category Protein Source E. coli Species Human

RAC3 Recombinant Protein - H00005881-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

Recombinant Human RAC3 Protein - NBP1-50927 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E.coli Species Human

RAC3-Antibody-Center-Blocking-Peptide - BP16138c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RAC3 Protein - GTX109266-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

RAC3 protein - 30R-1843 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

RAC3 (1-189) - AR09783PU-L from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

RAC3 (1-189) - AR09783PU-N from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

RAC3 - H00005881-P01-02 from Acris Antibodies Category Protein Prices $300.00 Sizes 2 µg Source in vitro transl. Species Human

Ras-Related C3 Botulinum Toxin Substrate 3, Human Recombinant - 228-12793-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 3 - 228-12793-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Ras-Related C3 Botulinum Toxin Substrate 3 - 228-12793-3 from RayBiotech Category Protein Prices $2,880.00 Sizes 3 µg Source Escherichia Coli. Species Human

RAC3, 1-189aa, Human, E.coli - 01-2107-3 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

RAC1/2/3 fusion protein - Ag9045 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

RAC1/2/3 fusion protein - Ag9064 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Recombinant Human RAC3 Protein - BP002407-PRO-073 from Syd Labs Category Protein Prices $160.00, $2,700.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

RAC3, 1-189aa, Recombinant Protein - GWB-P1195L from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

RAC3 Human Protein - GWB-BSP596 from Genway Biotech Category Protein Prices $75.00, $165.00, $3,230.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human RAC3, His-tagged - RAC3-1485H from Creative Biomart Category Protein Source E. coli.

Recombinant Human RAC3 - RAC3-3391H from Creative Biomart Category Protein Source E.coli.

Recombinant Human RAC3 - RAC3-31284TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human RAC3, His-tagged - RAC3-31286TH from Creative Biomart Category Protein Source E. coli

Recombinant Human RAC3, His-tagged - RAC3-2149H from Creative Biomart Category Protein Source E.coli Species Human

RAC3 1-189aa - CMB-676 from Reagent Proteins Category Protein Prices $469.00, $889.00 Sizes 100.00 µg, 500 µg Source E.coli Species Human

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