PRPF6

Gene Symbol PRPF6
Entrez Gene 24148
Alt Symbol ANT-1, ANT1, C20orf14, Prp6, RP60, SNRNP102, TOM, U5-102K, hPrp6
Species Human
Gene Type protein-coding
Description pre-mRNA processing factor 6
Other Description PRP6 homolog|PRP6 pre-mRNA processing factor 6 homolog|U5 snRNP-associated 102 kDa protein|U5-102 kDa protein|androgen receptor N-terminal domain transactivating protein-1|androgen receptor N-terminal domain-transactivating protein 1|p102 U5 small nuclear ribonucleoprotein particle-binding protein|pre-mRNA-processing factor 6|putative mitochondrial outer membrane protein import receptor
Swissprots Q5VXS5 Q9NTE6 Q9H4U8 B2RAR5 O95109 Q9H4T9 Q9H3Z1 B3KMC6 O94906
Accessions CAH05536 EAW75174 EAW75175 EAW75176 EAW75177 EAW75178 EAW75179 O94906 AB019219 BAA37140 AF026031 AAD01798 AF221842 AAF66128 AK001554 BAG50938 AK225993 AK314310 BAG36962 AL137320 CAB70695 BC001666 AAH01666 BI562505 BP366197 XM_006723769 XP_006723832 NM_012469 NP_036601
Function Involved in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. {ECO:0000269|PubMed:12039962}.
Subcellular Location Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:12039962}.
Top Pathways Spliceosome

PRP6 (B-1) - sc-166889 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRP6 (B-1): sc-166889. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and cytoplasmic localization.

PRP6 (C-12) - sc-271882 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRP6 (C-12): sc-271882. Western blot analysis of PRP6 expression in Jurkat (A) and K-562 (B) nuclear extracts.

PRP6 (D-3) - sc-271866 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRP6 (D-3): sc-271866. Western blot analysis of PRP6 expression in Jurkat (A), K-562 (B) and HL-60 (C) whole cell lysates.

PRP6 (D-4) - sc-166890 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRP6 (D-4): sc-166890. Western blot analysis of PRP6 expression in K-562 (A) and HL-60 (B) nuclear extracts.

PRP6 (H-300) - sc-48786 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PRP6 (H-300): sc-48786. Western blot analysis of PRP6 expression in K-562 (A) and HL-60 (B) nuclear extracts.

PRP6 (N-20) - sc-13253 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRP6 (N-20): sc-13253. Western blot analysis of PRP6 expression in K-562 (A) and Jurkat (B) nuclear extracts.

PRP6 (P-17) - sc-13254 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRP6 (P-17): sc-13254. Western blot analysis of PRP6 expression in K-562 (A) and Jurkat (B) nuclear extracts.

Anti-C20orf14 antibody - ab68627 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-C20orf14 antibody (ab68627) at 1/500 dilutionLane 1 : C20orf14 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-PRP6 antibody - ab124229 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PRP6 antibody (ab124229) at 1/100 dilution + CEM cell line lysate at 35 µg

Anti-PRPF6 / TOM Antibody (aa806-827, APC) - LS-C239489 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRPF6 / TOM Antibody (aa806-827, AP) - LS-C239488 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRPF6 / TOM Antibody (aa806-827, FITC) - LS-C239491 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRPF6 / TOM Antibody (aa806-827, Biotin) - LS-C239490 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRPF6 / TOM Antibody (aa806-827, PE) - LS-C239493 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRPF6 / TOM Antibody (aa806-827, Azide-free, HRP) - LS-C248561 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRPF6 / TOM Antibody (aa806-827) - LS-C324315 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRPF6 / TOM Antibody (aa747-796) - LS-C199496 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human colon carcinoma tissue, using PRPF6 Antibody. The sample on the right was incubated with synthetic peptide.

Anti-PRPF6 / TOM Antibody (aa51-100) - LS-C40320 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T Cell Lysate

Anti-PRPF6 / TOM Antibody (aa851-900) - LS-C40319 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
PRPF6 antibody LS-C40319 Western blot of Transfected 293T cell lysate.

Anti-PRPF6 / TOM Antibody (aa807-836) - LS-C162176 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PRPF6 Antibody western blot of CEM cell line lysates (35 ug/lane). The PRPF6 antibody detected the PRPF6 protein (arrow).

Anti-PRPF6 / TOM Antibody (aa1-50) - LS-C289487 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PRP6 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-PRP6 used at a dilution of 1:200 (1 Detection: DAB.

Anti-PRPF6 / TOM Antibody - LS-C334958 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of 293T cell lines, using PRPF6 antibody.

Anti-PRPF6 / TOM Antibody (aa150-200) - LS-C289488 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human PRP6 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-PRP6 used at a dilution of 1:1000 (0.2 Detection: DAB.

Anti-PRPF6 / TOM Antibody (aa196-229) - LS-C344387 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from mouse NIH/3T3 cell line with PRPF6 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

PRPF6 Antibody - NBP1-46212 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: PRPF6 Antibody [NBP1-46212] - Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-PRP6 used at a dilution of 1:200 (1ug/ml). Detection: DAB
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