Gene Symbol | PRPF6 |
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Entrez Gene | 24148 |
Alt Symbol | ANT-1, ANT1, C20orf14, Prp6, RP60, SNRNP102, TOM, U5-102K, hPrp6 |
Species | Human |
Gene Type | protein-coding |
Description | pre-mRNA processing factor 6 |
Other Description | PRP6 homolog|PRP6 pre-mRNA processing factor 6 homolog|U5 snRNP-associated 102 kDa protein|U5-102 kDa protein|androgen receptor N-terminal domain transactivating protein-1|androgen receptor N-terminal domain-transactivating protein 1|p102 U5 small nuclear ribonucleoprotein particle-binding protein|pre-mRNA-processing factor 6|putative mitochondrial outer membrane protein import receptor |
Swissprots | Q5VXS5 Q9NTE6 Q9H4U8 B2RAR5 O95109 Q9H4T9 Q9H3Z1 B3KMC6 O94906 |
Accessions | CAH05536 EAW75174 EAW75175 EAW75176 EAW75177 EAW75178 EAW75179 O94906 AB019219 BAA37140 AF026031 AAD01798 AF221842 AAF66128 AK001554 BAG50938 AK225993 AK314310 BAG36962 AL137320 CAB70695 BC001666 AAH01666 BI562505 BP366197 XM_006723769 XP_006723832 NM_012469 NP_036601 |
Function | Involved in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. {ECO:0000269|PubMed:12039962}. |
Subcellular Location | Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12039962}. |
Top Pathways | Spliceosome |
PRPF6 / TOM Antibody Blocking Peptide - LS-E3906 from LifeSpan Bioscience
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PRPF6-Antibody-C-term-Blocking-Peptide - BP16097b from Abgent, a WuXi AppTec company
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PRPF6 Blocking Peptide - 33R-3130 from Fitzgerald
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PRPF6 Blocking Peptide - 33R-7111 from Fitzgerald
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PRP6 Peptide - AC21-2822-P from Abcore
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PRPF6 fusion protein - ag13822 from Proteintech Group
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PRPF6 fusion protein - ag13817 from Proteintech Group
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Recombinant Human Pre-mRNA-processing factor 6(PRPF6) ,partial - CSB-YP018772HU CSB-EP018772HU CSB-BP018772HU CSB-MP018772HU from Cusabio
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ANT1/2/3/4 (45-233) - sc-4352 WB from Santa Cruz Biotechnology
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PRPF6 - TP300527 from Acris Antibodies
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Pre-mRNA-processing factor 6 (PRPF6), partial, Recombinant Protein - MBS1078795 from MyBioSource
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PRPF6, Peptide - MBS428402 from MyBioSource
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PRPF6 Recombinant Protein Antigen - NBP1-92298PEP from Novus Biologicals
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PRPF6 Blocking Peptide - abx061831 from Abbexa
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PRPF6-Blocking-Peptide-N-term - BP20777a from Abgent, a WuXi AppTec company
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PRPF6 Peptide, Human - M34GP12466H from Creative Peptides
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PRPF6 Blocking Peptide - CBP7221 from Cohesion Biosciences
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