PRPF6

Gene Symbol PRPF6
Entrez Gene 24148
Alt Symbol ANT-1, ANT1, C20orf14, Prp6, RP60, SNRNP102, TOM, U5-102K, hPrp6
Species Human
Gene Type protein-coding
Description pre-mRNA processing factor 6
Other Description PRP6 homolog|PRP6 pre-mRNA processing factor 6 homolog|U5 snRNP-associated 102 kDa protein|U5-102 kDa protein|androgen receptor N-terminal domain transactivating protein-1|androgen receptor N-terminal domain-transactivating protein 1|p102 U5 small nuclear ribonucleoprotein particle-binding protein|pre-mRNA-processing factor 6|putative mitochondrial outer membrane protein import receptor
Swissprots Q5VXS5 Q9NTE6 Q9H4U8 B2RAR5 O95109 Q9H4T9 Q9H3Z1 B3KMC6 O94906
Accessions CAH05536 EAW75174 EAW75175 EAW75176 EAW75177 EAW75178 EAW75179 O94906 AB019219 BAA37140 AF026031 AAD01798 AF221842 AAF66128 AK001554 BAG50938 AK225993 AK314310 BAG36962 AL137320 CAB70695 BC001666 AAH01666 BI562505 BP366197 XM_006723769 XP_006723832 NM_012469 NP_036601
Function Involved in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation. {ECO:0000269|PubMed:12039962}.
Subcellular Location Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:12039962}.
Top Pathways Spliceosome

PRP6 CRISPR/Cas9 KO Plasmid (h) - sc-406570 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRP6 HDR Plasmid (h) - sc-406570-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRP6 Double Nickase Plasmid (h) - sc-406570-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRP6 Double Nickase Plasmid (h2) - sc-406570-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRP6 CRISPR Activation Plasmid (h) - sc-406570-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRP6 CRISPR Activation Plasmid (h2) - sc-406570-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRP6 Lentiviral Activation Particles (h) - sc-406570-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRP6 Lentiviral Activation Particles (h2) - sc-406570-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRP6 siRNA (h) - sc-38207 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRP6 shRNA Plasmid (h) - sc-38207-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRP6 shRNA (h) Lentiviral Particles - sc-38207-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRPF6 RNAi - H00024148-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU029621 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17480 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

PRPF6 siRNA (Human) - CRH8476 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PRPF6 (NM_012469.3) - SHH383820 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PRPF6(NM_012469.3) - SHR142840 from Creative biogene

Category siRNA
Species Reactivities Human

Human PRPF6 siRNA - orb268978 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PRPF6 shRNA Plasmid (Human) - CHH8476 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PRPF6 miRNA 3'UTR clone - MiUTR1H-08319 from Creative biogene

Species Reactivities Human
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