Gene Symbol | FEZ1 |
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Entrez Gene | 9638 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | fasciculation and elongation protein zeta 1 (zygin I) |
Other Description | fasciculation and elongation protein zeta-1|zygin I|zygin-1 |
Swissprots | O00728 Q6IBI7 Q99689 O00679 |
Accessions | EAW67636 EAW67637 EAW67638 EAW67639 Q99689 AK296554 BAG59177 BC009545 AAH09545 BM663785 CN310685 CR456817 CAG33098 CR541954 CAG46752 DA697171 DQ890963 ABM81889 DQ894135 ABM85061 U60060 AAC51282 U60062 AAC51284 U69139 AAB40660 XM_005271734 XP_005271791 XM_005271735 XP_005271792 XM_011543071 XP_011541373 NM_005103 NP_005094 NM_022549 NP_072043 |
Function | May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules. {ECO:0000269|PubMed:20812761, ECO:0000269|PubMed:22354037}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18439996}. Cell membrane {ECO:0000250}. Note=Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity). {ECO:0000250}. |
Tissue Specificity | Mainly expressed in brain. |
FEZ1 Antibody - 14235 from Cell Signaling Technology
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zygin 1 (E-15) - sc-161278 from Santa Cruz Biotechnology
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Anti-Fez1 antibody - ab168919 from Abcam
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Anti-Fez1 antibody - ab168953 from Abcam
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Anti-FEZ1 Antibody - LS-C307523 from LifeSpan Bioscience
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Anti-FEZF1 / FEZ Antibody (aa464-475) - LS-C193969 from LifeSpan Bioscience
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Anti-FEZ1 Antibody - LS-C310358 from LifeSpan Bioscience
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Anti-FEZ1 Antibody (C-Terminus) - LS-C34715 from LifeSpan Bioscience
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Anti-FEZ1 Antibody (aa278-290) IHC-plus⢠- LS-B3602 from LifeSpan Bioscience
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FEZ1 Antibody - NBP1-86256 from Novus Biologicals
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FEZ1 Antibody - NB100-53816 from Novus Biologicals
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FEZ1 Antibody - NBP1-76395 from Novus Biologicals
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FEZ1 Antibody - H00009638-B02P from Novus Biologicals
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FEZ1 Antibody - H00009638-B01 from Novus Biologicals
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FEZ1 Polyclonal Antibody - bs-9721R from Bioss
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Anti-FEZ1 antibody produced in rabbit - SAB1411687 from Sigma-Aldrich
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Anti-FEZ1 antibody produced in rabbit - PRS4265 from Sigma-Aldrich
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Anti-FEZ1 antibody produced in mouse - SAB1406861 from Sigma-Aldrich
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Anti-FEZ1/ZYGIN 1 antibody produced in goat - SAB2500392 from Sigma-Aldrich
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FEZ1 Antibody - middle region (ARP63988_P050) - ARP63988_P050 from Aviva Systems Biology
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FEZ1--Zygin-1-Antibody - AF1409a from Abgent, a WuXi AppTec company
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FEZ1 antibody, Internal - GTX89222 from GeneTex
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FEZ1 antibody [C1C3] - GTX117376 from GeneTex
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FEZ1 antibody [N1C1] - GTX102009 from GeneTex
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FEZ1 antibody - orb74853 from Biorbyt
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