Gene Symbol | FEZ1 |
---|---|
Entrez Gene | 9638 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | fasciculation and elongation protein zeta 1 (zygin I) |
Other Description | fasciculation and elongation protein zeta-1|zygin I|zygin-1 |
Swissprots | O00728 Q6IBI7 Q99689 O00679 |
Accessions | EAW67636 EAW67637 EAW67638 EAW67639 Q99689 AK296554 BAG59177 BC009545 AAH09545 BM663785 CN310685 CR456817 CAG33098 CR541954 CAG46752 DA697171 DQ890963 ABM81889 DQ894135 ABM85061 U60060 AAC51282 U60062 AAC51284 U69139 AAB40660 XM_005271734 XP_005271791 XM_005271735 XP_005271792 XM_011543071 XP_011541373 NM_005103 NP_005094 NM_022549 NP_072043 |
Function | May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules. {ECO:0000269|PubMed:20812761, ECO:0000269|PubMed:22354037}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18439996}. Cell membrane {ECO:0000250}. Note=Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity). {ECO:0000250}. |
Tissue Specificity | Mainly expressed in brain. |
Human Fez1 full length protein - ab132344 from Abcam
|
||||||||||
FEZ1 Antibody Blocking Peptide - LS-E26210 from LifeSpan Bioscience
|
||||||||||
FEZ1 Antibody Blocking Peptide - LS-E30363 from LifeSpan Bioscience
|
||||||||||
Recombinant Human FEZ1 Protein - H00009638-P01 from Novus Biologicals
|
||||||||||
FEZ1 Blocking Peptide - NBP1-76395PEP from Novus Biologicals
|
||||||||||
FEZ1 blocking peptide - GTX89222-PEP from GeneTex
|
||||||||||
Fez1 Peptide - AC21-1041-P from Abcore
|
||||||||||
Zygin-1 - H00009638-P01-10 from Acris Antibodies
|
||||||||||
Zygin-1 - H00009638-P01-25 from Acris Antibodies
|
||||||||||
Zygin-1 Control Peptide - AP30333CP-N from Acris Antibodies
|
||||||||||
FEZ1 Peptide - 4265P from ProSci
|
||||||||||
FEZ1 Peptide - 45-586P from ProSci
|
||||||||||
FEZ1 fusion protein - Ag2744 from Proteintech Group
|
||||||||||
Recombinant Human FEZ1, GST-tagged - FEZ1-12849H from Creative Biomart
|
||||||||||
Recombinant Human Fasciculation and elongation protein zeta-1(FEZ1) - CSB-YP857870HU CSB-EP857870HU CSB-BP857870HU CSB-MP857870HU from Cusabio
|
||||||||||
FEZ1/Zygin 1, Peptide - MBS426531 from MyBioSource
|
||||||||||
FEZ1 Peptide, Human - M34GP05679H from Creative Peptides
|
||||||||||
Fasciculation and elongation protein zeta-1 (FEZ1), Recombinant Protein - MBS1462639 from MyBioSource
|
||||||||||
FEZ1 Immunizing peptide - orb16891 from Biorbyt
|