FEZ1

Gene Symbol FEZ1
Entrez Gene 9638
Alt Symbol -
Species Human
Gene Type protein-coding
Description fasciculation and elongation protein zeta 1 (zygin I)
Other Description fasciculation and elongation protein zeta-1|zygin I|zygin-1
Swissprots O00728 Q6IBI7 Q99689 O00679
Accessions EAW67636 EAW67637 EAW67638 EAW67639 Q99689 AK296554 BAG59177 BC009545 AAH09545 BM663785 CN310685 CR456817 CAG33098 CR541954 CAG46752 DA697171 DQ890963 ABM81889 DQ894135 ABM85061 U60060 AAC51282 U60062 AAC51284 U69139 AAB40660 XM_005271734 XP_005271791 XM_005271735 XP_005271792 XM_011543071 XP_011541373 NM_005103 NP_005094 NM_022549 NP_072043
Function May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules. {ECO:0000269|PubMed:20812761, ECO:0000269|PubMed:22354037}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18439996}. Cell membrane {ECO:0000250}. Note=Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity). {ECO:0000250}.
Tissue Specificity Mainly expressed in brain.

zygin 1 CRISPR/Cas9 KO Plasmid (h) - sc-411302 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

zygin 1 HDR Plasmid (h) - sc-411302-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

zygin 1 Double Nickase Plasmid (h) - sc-411302-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

zygin 1 Double Nickase Plasmid (h2) - sc-411302-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

zygin 1 CRISPR Activation Plasmid (h) - sc-411302-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

zygin 1 CRISPR Activation Plasmid (h2) - sc-411302-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

zygin 1 Lentiviral Activation Particles (h) - sc-411302-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

zygin 1 Lentiviral Activation Particles (h2) - sc-411302-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

zygin 1 siRNA (h) - sc-96452 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

zygin 1 shRNA Plasmid (h) - sc-96452-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

zygin 1 shRNA (h) Lentiviral Particles - sc-96452-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU035451 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8631 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8631 from Sigma-Aldrich

Category ZFN Kit
Prices $4,120.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08933 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08933

FEZ1 siRNA (Human) - CRH6416 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FEZ1 - MBS8205296 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FEZ1 (NM_005103.4) - SHH294182 from Creative biogene

Category siRNA
Species Reactivities Human

SignalSilence FEZ1 siRNA I - 72660 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from Malme-3M cells, transfected with 100 nM SignalSilence® Control siRNA (Unconjugated) #6568 (-) or SignalSilence ® FEZ1 siRNA I (+), using FEZ1 (D9R8Q) Rabbit mAb #42480 (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The FEZ1 (D9R8Q) Rabbit mAb confirms silencing of FEZ1 expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

Human FEZ1 siRNA - orb266918 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FEZ1 shRNA Plasmid (Human) - CHH6416 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FEZ1 miRNA 3'UTR clone - MiUTR3H-07126 from Creative biogene

Species Reactivities Human

FEZ1 miRNA 3'UTR clone - MiUTR3H-07127 from Creative biogene

Species Reactivities Human
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