ROS1

Gene Symbol	ROS1
Entrez Gene	6098
Alt Symbol	MCF3, ROS, c-ros-1
Species	Human
Gene Type	protein-coding
Description	ROS proto-oncogene 1 , receptor tyrosine kinase
Other Description	c-ros oncogene 1 , receptor tyrosine kinase|proto-oncogene c-Ros-1|proto-oncogene tyrosine-protein kinase ROS|transmembrane tyrosine-specific protein kinase|v-ros avian UR2 sarcoma virus oncogene homolog 1
Swissprots	Q15368 P08922 Q5TDB5
Accessions	AAA60277 EAW48208 EAW48209 P08922 BC144556 BC166687 AAI66687 M13880 AAA36580 M34353 AAA60278 XM_006715548 XP_006715611 XM_011536049 XP_011534351 XM_011536050 XP_011534352 XM_011536051 XP_011534353 XM_011536052 XP_011534354 XM_011536053 XP_011534355 XM_011536054 XP_011534356 XM_011536055 XP_011534357 XM_011536056 XP_011534358 XM_011536057 XP_011534359 XM_011536058 XP_011534360 NM_002944 NP_002935
Function	Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2. {ECO:0000269|PubMed:11094073, ECO:0000269|PubMed:16885344}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Expressed in brain. Expression is increased in primary gliomas. {ECO:0000269|PubMed:8143271}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PathScan ® Total ROS1 Sandwich ELISA Kit - 7091 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

PathScan ® Phospho-ROS1 (panTyr) Sandwich ELISA Kit - 7093 from Cell Signaling Technology Category ELISA Kit Prices $489.00 Sizes 1 kit (96 assays)

Rat ROS1 / ROS ELISA Kit (Sandwich ELISA) - LS-F9759 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 6.6 pg/ml Range 15.63-1000 pg/ml

Phosphotyrosine ROS1 ELISA Kit - RAB0990 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

C-ros oncogene 1, receptor tyrosine kinase (ROS1), Human, ELISA Kit - E01C2423 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Human ROS ELISA Kit - HR0028 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ROS ELISA Kit - AR0028 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

ROS, ELISA Kit - MBS2515781 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Human ROS(Reactive OXyen Species) ELISA Kit - E-EL-H5436 from Elabscience Category ELISA Kit Sensitivity 0.094ng/mL Range 0.156~10ng/mL

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7217431 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7213097 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 pg/mL.

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7232591 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-Ros Oncogene 1, Receptor Tyrosine Kinase (ROS1), ELISA Kit - MBS2021712 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 6.6pg/mL. Range 15.63-1000pg/mL

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7230557 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7233660 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7220095 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7246992 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7238064 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7213238 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

C-Ros Oncogene 1, Receptor Tyrosine Kinase (ROS1), ELISA Kit - MBS2024899 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.054ng/mL. Range 0.156-10ng/mL

c-ros oncogene 1, receptor tyrosine kinase (ROS1), ELISA Kit - MBS7209676 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for C-Ros Oncogene 1, Receptor Tyrosine Kinase (ROS1) - SEE273Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for C-Ros Oncogene 1, Receptor Tyrosine Kinase (ROS1) - SEE273Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.6pg/mL. Range 15.63-1000pg/mL The standard curve concentrations used for the ELISA’s were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.63pg/mL

ELISA Kit for C-Ros Oncogene 1, Receptor Tyrosine Kinase (ROS1) - SEE273Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human ROS(Reactive OXyen Species) ELISA Kit - E-EL-H5436 from Iwai North America Inc. Category ELISA Kit Prices $649.00 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156--10ng/mL

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