DAPP1

Gene Symbol DAPP1
Entrez Gene 27071
Alt Symbol BAM32
Species Human
Gene Type protein-coding
Description dual adaptor of phosphotyrosine and 3-phosphoinositides
Other Description B-cell adapter molecule of 32 kDa|b lymphocyte adapter protein Bam32|dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide|hDAPP1
Swissprots Q9UHF2 Q9UN19 Q8TCK5
Accessions EAX06108 EAX06109 EAX06110 EAX06111 Q9UN19 AF161551 AAF29038 AF163254 AAD49697 AF178987 AAF44351 AF186022 AAF14578 AK301355 BAG62900 AL713793 CAD28547 BC012924 AAH12924 BM968883 CA428013 DN995752 DQ893576 ABM84502 DQ894665 ABM85591 XM_011531840 XP_011530142 XM_011531841 XP_011530143 XM_011531842 XP_011530144 XM_011531843 XP_011530145 XR_938719 NM_001306151 NP_001293080 NM_014395 NP_055210
Function May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR)-signaling downstream of PI3K. {ECO:0000269|PubMed:10770799}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10770799}. Membrane {ECO:0000269|PubMed:10770799}; Peripheral membrane protein {ECO:0000269|PubMed:10770799}. Note=Membrane-associated after cell stimulation leading to its translocation.
Tissue Specificity Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells. {ECO:0000269|PubMed:10432293}.
Top Pathways B cell receptor signaling pathway

Human DAPP1 full length protein - ab162069 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162069 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human DAPP1 full length protein - ab162070 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162070 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human DAPP1 protein fragment - ab162071 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162071 on a 12.5% SDS-PAGE stained with Coomassie Blue.

DAPP1 / BAM32 Antibody Blocking Peptide - LS-E4985 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

DAPP1 / BAM32 Antibody Blocking Peptide - LS-E25220 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

DAPP1 / BAM32 Antibody Blocking Peptide - LS-E19865 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

DAPP1 / BAM32 Antibody Blocking Peptide - LS-E19866 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human DAPP1 Protein - H00027071-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

DAPP1 Recombinant Protein - H00027071-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human DAPP1 Protein - H00027071-P02 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

DAPP1-Antibody-C-term-Blocking-Peptide - BP17383b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

DAPP1 blocking peptide - GTX89948-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

DAPP1 Blocking Peptide - 33R-4412 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

DAPP1 Blocking Peptide - 33R-8628 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

DAPP1 Peptide - AC21-0042-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

DAPP1 Peptide - AC21-2027-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

DAPP1 - H00027071-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

DAPP1 - H00027071-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

DAPP1 - H00027071-P02 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

DAPP1 - H00027071-P02-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

DAPP1 - H00027071-P02-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

DAPP1 - H00027071-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

DAPP1 - H00027071-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

DAPP1 Peptide - 42-779P from ProSci

Category Peptide
Species Human

DAPP1 Peptide - 42-722P from ProSci

Category Peptide
Species Human
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