Gene Symbol | DAPP1 |
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Entrez Gene | 27071 |
Alt Symbol | BAM32 |
Species | Human |
Gene Type | protein-coding |
Description | dual adaptor of phosphotyrosine and 3-phosphoinositides |
Other Description | B-cell adapter molecule of 32 kDa|b lymphocyte adapter protein Bam32|dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide|hDAPP1 |
Swissprots | Q9UHF2 Q9UN19 Q8TCK5 |
Accessions | EAX06108 EAX06109 EAX06110 EAX06111 Q9UN19 AF161551 AAF29038 AF163254 AAD49697 AF178987 AAF44351 AF186022 AAF14578 AK301355 BAG62900 AL713793 CAD28547 BC012924 AAH12924 BM968883 CA428013 DN995752 DQ893576 ABM84502 DQ894665 ABM85591 XM_011531840 XP_011530142 XM_011531841 XP_011530143 XM_011531842 XP_011530144 XM_011531843 XP_011530145 XR_938719 NM_001306151 NP_001293080 NM_014395 NP_055210 |
Function | May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR)-signaling downstream of PI3K. {ECO:0000269|PubMed:10770799}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:10770799}. Membrane {ECO:0000269|PubMed:10770799}; Peripheral membrane protein {ECO:0000269|PubMed:10770799}. Note=Membrane-associated after cell stimulation leading to its translocation. |
Tissue Specificity | Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells. {ECO:0000269|PubMed:10432293}. |
Top Pathways | B cell receptor signaling pathway |
Human DAPP1 full length protein - ab162069 from Abcam
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Human DAPP1 full length protein - ab162070 from Abcam
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Human DAPP1 protein fragment - ab162071 from Abcam
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DAPP1 / BAM32 Antibody Blocking Peptide - LS-E4985 from LifeSpan Bioscience
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DAPP1 / BAM32 Antibody Blocking Peptide - LS-E25220 from LifeSpan Bioscience
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DAPP1 / BAM32 Antibody Blocking Peptide - LS-E19865 from LifeSpan Bioscience
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DAPP1 / BAM32 Antibody Blocking Peptide - LS-E19866 from LifeSpan Bioscience
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Recombinant Human DAPP1 Protein - H00027071-Q01 from Novus Biologicals
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DAPP1 Recombinant Protein - H00027071-P01 from Novus Biologicals
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Recombinant Human DAPP1 Protein - H00027071-P02 from Novus Biologicals
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DAPP1-Antibody-C-term-Blocking-Peptide - BP17383b from Abgent, a WuXi AppTec company
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DAPP1 blocking peptide - GTX89948-PEP from GeneTex
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DAPP1 Blocking Peptide - 33R-4412 from Fitzgerald
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DAPP1 Blocking Peptide - 33R-8628 from Fitzgerald
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DAPP1 Peptide - AC21-0042-P from Abcore
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DAPP1 Peptide - AC21-2027-P from Abcore
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DAPP1 - H00027071-P01-10 from Acris Antibodies
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DAPP1 - H00027071-P01-25 from Acris Antibodies
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DAPP1 - H00027071-P02 from Acris Antibodies
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DAPP1 - H00027071-P02-10 from Acris Antibodies
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DAPP1 - H00027071-P02-25 from Acris Antibodies
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DAPP1 - H00027071-Q01-10 from Acris Antibodies
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DAPP1 - H00027071-Q01-25 from Acris Antibodies
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DAPP1 Peptide - 42-779P from ProSci
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DAPP1 Peptide - 42-722P from ProSci
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