DAPP1

Gene Symbol DAPP1
Entrez Gene 27071
Alt Symbol BAM32
Species Human
Gene Type protein-coding
Description dual adaptor of phosphotyrosine and 3-phosphoinositides
Other Description B-cell adapter molecule of 32 kDa|b lymphocyte adapter protein Bam32|dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide|hDAPP1
Swissprots Q9UHF2 Q9UN19 Q8TCK5
Accessions EAX06108 EAX06109 EAX06110 EAX06111 Q9UN19 AF161551 AAF29038 AF163254 AAD49697 AF178987 AAF44351 AF186022 AAF14578 AK301355 BAG62900 AL713793 CAD28547 BC012924 AAH12924 BM968883 CA428013 DN995752 DQ893576 ABM84502 DQ894665 ABM85591 XM_011531840 XP_011530142 XM_011531841 XP_011530143 XM_011531842 XP_011530144 XM_011531843 XP_011530145 XR_938719 NM_001306151 NP_001293080 NM_014395 NP_055210
Function May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR)-signaling downstream of PI3K. {ECO:0000269|PubMed:10770799}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10770799}. Membrane {ECO:0000269|PubMed:10770799}; Peripheral membrane protein {ECO:0000269|PubMed:10770799}. Note=Membrane-associated after cell stimulation leading to its translocation.
Tissue Specificity Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells. {ECO:0000269|PubMed:10432293}.
Top Pathways B cell receptor signaling pathway

BAM32 CRISPR/Cas9 KO Plasmid (h) - sc-404873 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAM32 HDR Plasmid (h) - sc-404873-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAM32 Double Nickase Plasmid (h) - sc-404873-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAM32 Double Nickase Plasmid (h2) - sc-404873-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAM32 CRISPR Activation Plasmid (h) - sc-404873-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAM32 CRISPR Activation Plasmid (h2) - sc-404873-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAM32 Lentiviral Activation Particles (h) - sc-404873-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAM32 Lentiviral Activation Particles (h2) - sc-404873-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAM32 siRNA (h) - sc-60241 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BAM32 shRNA Plasmid (h) - sc-60241-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BAM32 shRNA (h) Lentiviral Particles - sc-60241-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DAPP1 RNAi - H00027071-R03 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU044801 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6931 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6931 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10955 from Sigma-Aldrich

Category miRNA

DAPP1 siRNA (Human) - CRH8946 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DAPP1 - MBS8203843 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DAPP1 (NM_014395.2) - SHH274581 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DAPP1(NM_014395.2) - SHG221743 from Creative biogene

Category siRNA
Species Reactivities Human

Human DAPP1 siRNA - orb269448 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DAPP1 shRNA Plasmid (Human) - CHH8946 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DAPP1 miRNA 3'UTR clone - MiUTR1H-02669 from Creative biogene

Species Reactivities Human
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