ZNRF2

Gene Symbol ZNRF2
Entrez Gene 223082
Alt Symbol RNF202
Species Human
Gene Type protein-coding
Description zinc and ring finger 2, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase ZNRF2|RING finger protein 202|protein Ells2|zinc finger/RING finger 2|zinc/RING finger protein 2
Swissprots Q8NHG8
Accessions EAL24455 EAW93938 EAW93939 Q8NHG8 AF513707 AAQ08115 AF527533 AAM88868 AK025240 AY054122 AAL14867 BC172400 AAI72400 XM_011515217 XP_011513519 XM_011515218 XP_011513520 XR_926925 NM_147128 NP_667339
Function May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. {ECO:0000269|PubMed:14561866}.
Subcellular Location Endosome membrane {ECO:0000269|PubMed:14561866}; Peripheral membrane protein {ECO:0000269|PubMed:14561866}. Lysosome membrane {ECO:0000269|PubMed:14561866}; Peripheral membrane protein {ECO:0000269|PubMed:14561866}. Cell junction, synapse, presynaptic cell membrane {ECO:0000269|PubMed:14561866}; Peripheral membrane protein {ECO:0000269|PubMed:14561866}. Note=Present in presynaptic plasma membranes in neurons.
Tissue Specificity Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney. {ECO:0000269|PubMed:14561866}.

ZNRF2 (T-13) - sc-138741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
ZNRF2 (T-13): sc-138741. Western blot analysis of ZNRF2 expression in non-transfected 293T: sc-117752 (A), human ZNRF2 transfected 293T: sc-372193 (B), Jurkat (C) and IMR-32 (D) whole cell lysates.

ZNRF2 (D-16) - sc-101876 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ZNRF2 antibody - ab86778 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZNRF2 antibody (ab86778) at 0.4 µg/mlLane 1 : HeLa cell lysate at 50 µgLane 2 : HeLa cell lysate at 15 µgLane 3 : HeLa cell lysate at 5 µgLane 4 : 293T cell lysate at 50 µgdeveloped using the ECL technique

Anti-ZNRF2 antibody - ab114098 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Rabbit anti-ZNRF2 antibody, at 1 µg/ml, staining ZNRF2 in HeLa whole cell lysate immunoprecipitated using ab114098 at 10 µg/mg lysate (1 mg for IP; 20% of IP loaded/lane). Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-ZNRF2 antibody - ab199932 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZNRF2 antibody (ab199932) at 1/1000 dilutionLane 1 : HeLa total cell extractLane 2 : Jurkat total cell extract

Anti-ZNRF2 antibody [EPR11399(B)] - ab156011 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11399(B)
All lanes : Anti-ZNRF2 antibody [EPR11399(B)] (ab156011) at 1/1000 dilutionLane 1 : Jurkat lysateLane 2 : HeLa lysateLane 3 : Human fetal brain lysate Lane 4 : Neuro-2a lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-ZNRF2 Antibody (aa115-130) - LS-C40744 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ZNRF2 Antibody (aa192-242) - LS-C289062 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNRF2 Antibody (aa100-150) - LS-C289063 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNRF2 Antibody (aa161-210) - LS-C119942 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using ZNRF2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-ZNRF2 Antibody (aa2-36) - LS-C344621 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from HeLa cell line with ZNRF2 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

ZNRF2 Antibody - NBP1-68484 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ZNRF2 Antibody [NBP1-68484] - Analysis of A549 cells, using ZNRF2 Antibody. The picture on the right is treated with the synthesized peptide.

ZNRF2 Antibody - NBP1-28715 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZNRF2 Antibody [NBP1-28715] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-ZNRF2 antibody NBP1-28715 used for WB at 0.4 ug/ml (A) and 1 ug/ml (B) and used for IP at 10 ug/mg lysate. ZNRF2 was also immunoprecipitated by rabbit anti-ZNRF2 antibody NBP1-28697, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

ZNRF2 Antibody - NBP1-28697 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: ZNRF2 Antibody [NBP1-28697] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-ZNRF2 antibody NBP1-28697 used for IP at 10 ug/mg lysate. ZNRF2 was also immunoprecipitated by rabbit anti-ZNRF2 antibody NBP1-28715, which recognizes a downstream epitope. For blotting immunoprecipitated ZNRF2, NBP1-28715 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

ZNRF2 Antibody - H00223082-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

ZNRF2 Polyclonal Antibody - bs-9140R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ZNRF2, C-Terminal antibody produced in rabbit - SAB4500880 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-ZNRF2, C-Terminal: <B>Cat. No. SAB4500880</B>: Immunofluorescence of A549 cells using Anti-ZNRF2, C-Terminal antibody. Cells on the left were treated with the Anti-ZNRF2, C-Terminal antibody. Cells on the right (negative control) were treated with both Anti-ZNRF2, C-Terminal antibody and the synthesized immunogen peptide.

ZNRF2-Antibody-N-term - AP20753a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from Hela cell line, using ZNRF2 Antibody (N-term)(Cat. #AP20753a). AP20753a was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

ZNRF2 Antibody (OAAF03626) - OAAF03626 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ZNRF2 antibody - 70R-21752 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Zinc And Ring Finger 2 Antibody - abx116712 from Abbexa

Host Rabbit
Clonality Polyclonal

ZNRF2 / RNF202 antibody - 20200-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal

ZNRF2 / RNF202 antibody - H00223082-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-ZNRF2 antibody - STJ96351 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

ZNRF2-Specific antibody - 20200-1-AP from Proteintech Group

Prices $279.00
Sizes con: 37 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse kidney tissue were subjected to SDS PAGE followed by western blot with 20200-1-AP( ZNRF2-Specific Antibody) at dilution of 1:300
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