ZNRF2

Gene Symbol ZNRF2
Entrez Gene 223082
Alt Symbol RNF202
Species Human
Gene Type protein-coding
Description zinc and ring finger 2, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase ZNRF2|RING finger protein 202|protein Ells2|zinc finger/RING finger 2|zinc/RING finger protein 2
Swissprots Q8NHG8
Accessions EAL24455 EAW93938 EAW93939 Q8NHG8 AF513707 AAQ08115 AF527533 AAM88868 AK025240 AY054122 AAL14867 BC172400 AAI72400 XM_011515217 XP_011513519 XM_011515218 XP_011513520 XR_926925 NM_147128 NP_667339
Function May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. {ECO:0000269|PubMed:14561866}.
Subcellular Location Endosome membrane {ECO:0000269|PubMed:14561866}; Peripheral membrane protein {ECO:0000269|PubMed:14561866}. Lysosome membrane {ECO:0000269|PubMed:14561866}; Peripheral membrane protein {ECO:0000269|PubMed:14561866}. Cell junction, synapse, presynaptic cell membrane {ECO:0000269|PubMed:14561866}; Peripheral membrane protein {ECO:0000269|PubMed:14561866}. Note=Present in presynaptic plasma membranes in neurons.
Tissue Specificity Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney. {ECO:0000269|PubMed:14561866}.

Human ZNRF2 protein fragment - ab166001 from Abcam

Category Protein
Source Wheat germ
Species Human
ab166001 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human ZNRF2 Protein - H00223082-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

ZNRF2 / RNF202 - H00223082-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

ZNRF2 / RNF202 - H00223082-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Recombinant Human ZNRF2, GST-tagged - ZNRF2-135H from Creative Biomart

Category Protein
Source E. coli
Species Human

Recombinant Human E3 ubiquitin-protein ligase ZNRF2(ZNRF2) - CSB-YP847746HU CSB-EP847746HU CSB-BP847746HU CSB-MP847746HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

ZNRF2-Blocking-Peptide-N-term - BP20753a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

ZNRF2 Peptide, Human - M34GP18367H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

ZNRF2 Blocking Peptide - CBP5335 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat, Zebrafish

E3 ubiquitin-protein ligase ZNRF2 (ZNRF2), Recombinant Protein - MBS1303820 from MyBioSource

Category Protein
Prices $990.00, $990.00, $1,220.00, $1,220.00, $1,510.00, $1,510.00, $1,975.00, $1,975.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
Search more