Gene Symbol | CTU2 |
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Entrez Gene | 348180 |
Alt Symbol | C16orf84, NCS2, UPF0432 |
Species | Human |
Gene Type | protein-coding |
Description | cytosolic thiouridylase subunit 2 homolog (S. pombe) |
Other Description | cytoplasmic tRNA 2-thiolation protein 2 |
Swissprots | Q66K78 Q86SV4 Q0P511 B2RXK0 Q6P4C8 Q2VPK5 |
Accessions | EAW66775 EAW66776 EAW66777 EAW66778 EAW66779 EAW66780 Q2VPK5 AK299521 BAG61472 BC021056 BC021829 BC044951 BC063512 BC080540 AAH80540 BC108659 AAI08660 BC121805 AAI21806 BC125269 AAI25270 BC157881 AAI57882 BM554780 BQ430809 XM_011523068 XP_011521370 NM_001012759 NP_001012777 NM_001012762 NP_001012780 |
Function | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. {ECO:0000255|HAMAP-Rule:MF_03054, ECO:0000269|PubMed:19017811}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Sulfur relay system |
CTU2 (E-12) - sc-164891 from Santa Cruz Biotechnology
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Anti-CTU2 antibody - ab122754 from Abcam
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Anti-CTU2 antibody [EPR11194] - ab177160 from Abcam
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CTU2 Antibody - NBP1-88457 from Novus Biologicals
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CTU2 Antibody - NBP1-88456 from Novus Biologicals
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Anti-CTU2 antibody produced in rabbit - HPA041894 from Sigma-Aldrich
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Anti-CTU2 antibody produced in rabbit - HPA041135 from Sigma-Aldrich
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CTU2 antibody - 23337-1-AP from Acris Antibodies
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C16orf84 antibody - 23337-1-AP from Proteintech Group
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Anti-CTU2 polyclonal antibody - DPABH-21048 from Creative Diagnostics
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CTU2 antibody (FITC) - orb187116 from Biorbyt
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C16orf84, Polyclonal Antibody - MBS767270 from MyBioSource
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anti-C16orf84 antibody - A001038 from Biobool
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CTU2 Polyclonal Antibody - A13003 from ABclonal
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