| Gene Symbol | CTU2 |
|---|---|
| Entrez Gene | 348180 |
| Alt Symbol | C16orf84, NCS2, UPF0432 |
| Species | Human |
| Gene Type | protein-coding |
| Description | cytosolic thiouridylase subunit 2 homolog (S. pombe) |
| Other Description | cytoplasmic tRNA 2-thiolation protein 2 |
| Swissprots | Q66K78 Q86SV4 Q0P511 B2RXK0 Q6P4C8 Q2VPK5 |
| Accessions | EAW66775 EAW66776 EAW66777 EAW66778 EAW66779 EAW66780 Q2VPK5 AK299521 BAG61472 BC021056 BC021829 BC044951 BC063512 BC080540 AAH80540 BC108659 AAI08660 BC121805 AAI21806 BC125269 AAI25270 BC157881 AAI57882 BM554780 BQ430809 XM_011523068 XP_011521370 NM_001012759 NP_001012777 NM_001012762 NP_001012780 |
| Function | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. {ECO:0000255|HAMAP-Rule:MF_03054, ECO:0000269|PubMed:19017811}. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Sulfur relay system |
Human CTU2 cDNA clone(NM_001012759.1) - CDFH004510 from Creative Biomart
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Human CTU2 cDNA clone(NM_001012762.1) - CDFH004511 from Creative Biomart
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Human CTU2 ORF clone(NM_001012762.1) - CDCH384467 from Creative Biomart
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Human CTU2 ORF Clone(NM_001012759.1) - CDCR341131 from Creative Biomart
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Human CTU2 ORF Clone(NM_001012762.1) - CDCR341134 from Creative Biomart
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Human CTU2 ORF Clone(NM_001012762.1) - CDCR341135 from Creative Biomart
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Human CTU2 ORF Clone(NM_001012759.1) - CDCR341299 from Creative Biomart
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Human CTU2 ORF Clone(NM_001012759.1) - CDCR341300 from Creative Biomart
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Human CTU2 ORF clone (NM_001012759.1) - CDCR037058 from Creative biogene
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Human CTU2 ORF clone (NM_001012762.1) - CDCR037060 from Creative biogene
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Human CTU2 ORF Clone (BC125269) - CDCS418390 from Creative biogene
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Human CTU2 cDNA Clone(NM_001012759.1) - CDFH004510 from Creative biogene
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Human CTU2 cDNA Clone(NM_001012762.1) - CDFH004511 from Creative biogene
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