CDCA8

Gene Symbol CDCA8
Entrez Gene 55143
Alt Symbol BOR, BOREALIN, DasraB, MESRGP
Species Human
Gene Type protein-coding
Description cell division cycle associated 8
Other Description Dasra B|borealin|cell division cycle-associated protein 8|dasra-B|hDasra-B|pluripotent embryonic stem cell-related gene 3 protein
Swissprots Q96AM3 D3DPT4 Q9NVW5 Q53HN1 Q53HL2
Accessions EAX07324 EAX07325 Q53HL2 AK001330 BAA91629 AK022104 BAB13961 AK022606 BAB14125 AK026423 AK222549 BAD96269 AK222568 BAD96288 AK291917 BAF84606 AK302116 BAG63495 AY508815 AAR91699 BC000703 AAH00703 BC001651 AAH01651 BC008079 AAH08079 BC016944 AAH16944 HQ447173 ADQ31660 NM_001256875 NP_001243804 NM_018101 NP_060571
Function Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment. {ECO:0000269|PubMed:15249581, ECO:0000269|PubMed:15260989, ECO:0000269|PubMed:16571674, ECO:0000269|PubMed:18243099}.
Subcellular Location Nucleus, nucleolus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with SENP3 in the nucleolus in interphase cells.

Borealin CRISPR/Cas9 KO Plasmid (h) - sc-403003 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Borealin HDR Plasmid (h) - sc-403003-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Borealin Double Nickase Plasmid (h) - sc-403003-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Borealin Double Nickase Plasmid (h2) - sc-403003-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Borealin CRISPR Activation Plasmid (h) - sc-403003-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Borealin CRISPR Activation Plasmid (h2) - sc-403003-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Borealin Lentiviral Activation Particles (h) - sc-403003-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Borealin Lentiviral Activation Particles (h2) - sc-403003-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Borealin siRNA (h) - sc-60277 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Borealin shRNA Plasmid (h) - sc-60277-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Borealin shRNA (h) Lentiviral Particles - sc-60277-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Borealin RNAi - H00055143-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU046531 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5804 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5804 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CDCA8 siRNA (Human) - CRJ0500 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDCA8 - MBS8218159 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CDCA8 (NM_018101.3) - SHH260073 from Creative biogene

Category siRNA
Species Reactivities Human

Human CDCA8 siRNA - orb271001 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDCA8 shRNA Plasmid (Human) - CHJ0500 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CDCA8 miRNA 3'UTR clone - MiUTR3H-10933 from Creative biogene

Species Reactivities Human
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