NEK8

Gene Symbol	NEK8
Entrez Gene	284086
Alt Symbol	JCK, NEK12A, NPHP9, RHPD2
Species	Human
Gene Type	protein-coding
Description	NIMA-related kinase 8
Other Description	NIMA (never in mitosis gene a)- related kinase 8|NIMA-family kinase NEK8|NIMA-related kinase 12a|nephrocystin 9|never in mitosis A-related kinase 8|nimA-related protein kinase 8|nima-related protein kinase 12a|serine/threonine-protein kinase Nek8|serine/thrionine-protein kinase NEK8
Swissprots	Q8NDH1 Q14CL7 A6NIC5 Q86SG6 Q2M1S6
Accessions	EAW51135 EAW51136 EAW51137 Q86SG6 AK301429 BAG62957 AL833909 CAD38765 AY242354 AAO88243 AY267371 AAP04006 BC112240 AAI12241 BC113705 AAI13706 HQ258347 ADR83101 XM_011524638 XP_011522940 XM_011524639 XP_011522941 XM_011524640 XP_011522942 XM_011524641 XP_011522943 XM_011524642 XP_011522944 XM_011524643 XP_011522945 XM_011524644 XP_011522946 XM_011524645 XP_011522947 XR_934448 NM_178170 NP_835464
Function	Required for renal tubular integrity. May regulate local cytoskeletal structure in kidney tubule epithelial cells. May regulate ciliary biogenesis through targeting of proteins to the cilia (By similarity). Plays a role in organogenesis and is involved in the regulation of the Hippo signaling pathway. {ECO:0000250, ECO:0000269|PubMed:23418306}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton. Cell projection, cilium {ECO:0000250}. Note=Predominantly cytoplasmic. Localizes to the proximal region of the primary cilium and is not observed in dividing cells.
Tissue Specificity	Highest expression in thyroid, adrenal gland and skin. Low levels in spleen, colon and uterus. Overexpressed in breast tumors, with highest expression in infiltrating ductal carcinomas and moderate levels in mucinous adenocarcinoma. {ECO:0000269|PubMed:15019993}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NEK8 full length protein - ab166159 from Abcam Category Protein Source Wheat germ Species Human

Human NEK8 protein fragment - ab166160 from Abcam Category Protein Source Wheat germ Species Human

NEK8 Antibody Blocking Peptide - LS-E2817 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NEK8 Antibody Blocking Peptide - LS-E8684 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NEK8 Antibody Blocking Peptide - LS-E8685 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NEK8 Protein - H00284086-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human NEK8 Protein - H00284086-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NEK8 Peptide - P2225 from Novus Biologicals Category Peptide Species Human

NEK8 Peptide - P2224 from Novus Biologicals Category Peptide Species Human

NEK8-Antibody-C-term-Blocking-Peptide - BP7095b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NEK8-Antibody-N-term-Blocking-Peptide - BP7095a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NEK8 - H00284086-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

NEK8 - H00284086-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

NEK8 - H00284086-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

NEK8 - H00284086-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NEK8 - H00284086-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human Serine/threonine-protein kinase Nek8(NEK8) - CSB-YP801219HU CSB-EP801219HU CSB-BP801219HU CSB-MP801219HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Active human NEK8 protein fragment - ab204141 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

NEK8 Peptide, Human - M34GP10294H from Creative Peptides Category Peptide Source Synthetic. Species Human

NEK8 Recombinant Protein Antigen - NBP1-82540PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NEK8 Recombinant Protein Antigen - NBP1-82539PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Serine/threonine-protein kinase Nek8 (NEK8), Recombinant Protein - MBS1466375 from MyBioSource Category Protein Prices $1,495.00, $1,495.00, $1,725.00, $1,725.00, $2,560.00, $2,560.00, $3,000.00, $3,000.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more