Gene Symbol | F11 |
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Entrez Gene | 2160 |
Alt Symbol | FXI |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor XI |
Other Description | PTA|plasma thromboplastin antecedent |
Swissprots | P03951 Q9Y495 D3DP64 Q4W5C2 |
Accessions | AAA51985 AAN85554 AAY40901 BAA20295 EAX04619 EAX04620 EAX04621 P03951 AF045649 AAC24506 AK313195 BC020617 BC029374 BC119014 AAI19015 BC122863 AAI22864 DA630863 M13142 AAA52487 XM_005262821 XP_005262878 XM_005262822 XP_005262879 XM_005262823 XP_005262880 XM_005262824 XP_005262881 XM_006714137 XP_006714200 XR_938706 XR_938707 NM_000128 NP_000119 NM_019559 |
Function | Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. |
Subcellular Location | Secreted. |
Tissue Specificity | Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells. |
Top Pathways | Complement and coagulation cascades |
F11-Over-expression-Lysate - LY12690a from Abgent, a WuXi AppTec company
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F11 293T Cell Transient Overexpression Lysate(Denatured) - H00002160-T01 from Acris Antibodies
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F11 overexpression lysate - LY400043 from Acris Antibodies
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F11 293 Cell Lysate - 400138 from ABBIOTEC
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Coagulation Factor XI Overexpression Lysate (Denatured) - H00002160-T01 from Novus Biologicals
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F11 Over-expression Lysate Product - GWB-2E15A7 from Genway Biotech
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Human Coagulation Factor XI / FXI / F11 HEK293 Cell Lysate (WB positive control) - 10302-H08HL-300 from Sino Biological
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Human Factor XI (Factor 11) Deficient Plasma (EDTA) - D101104 from AssayPro
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Human Factor XI (Factor 11) Deficient Plasma (EDTA) - D101105 from AssayPro
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Human Factor XI (Factor 11) Deficient Plasma (EDTA) - D101106 from AssayPro
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Human Factor XI (Factor 11) Deficient Plasma (Heparin) - D101107 from AssayPro
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Human Factor XI (Factor 11) Deficient Plasma (Heparin) - D101108 from AssayPro
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Human Factor XI (Factor 11) Deficient Plasma (Heparin) - D101109 from AssayPro
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Human Factor XI (Factor 11) Deficient Plasma (Sodium Citrate) - D101101 from AssayPro
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Human Factor XI (Factor 11) Deficient Plasma (Sodium Citrate) - D101102 from AssayPro
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Human Factor XI (Factor 11) Deficient Plasma (Sodium Citrate) - D101103 from AssayPro
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Human Factor XI (Factor 11) Deficient Serum - D101110 from AssayPro
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Human Factor XI (Factor 11) Deficient Serum - D101111 from AssayPro
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Human Factor XI (Factor 11) Deficient Serum - D101112 from AssayPro
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Coagulation Factor XI Overexpression Lysate (Native) - NBL1-10403 from Novus Biologicals
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Human F11 Human Cells Transfected Lysate (positive control) (denatured) - orb173164 from Biorbyt
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Panoply™ Human F11 Knockdown Stable Cell Line - CSC-DC005165 from Creative biogene
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