Gene Symbol | F11 |
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Entrez Gene | 2160 |
Alt Symbol | FXI |
Species | Human |
Gene Type | protein-coding |
Description | coagulation factor XI |
Other Description | PTA|plasma thromboplastin antecedent |
Swissprots | P03951 Q9Y495 D3DP64 Q4W5C2 |
Accessions | AAA51985 AAN85554 AAY40901 BAA20295 EAX04619 EAX04620 EAX04621 P03951 AF045649 AAC24506 AK313195 BC020617 BC029374 BC119014 AAI19015 BC122863 AAI22864 DA630863 M13142 AAA52487 XM_005262821 XP_005262878 XM_005262822 XP_005262879 XM_005262823 XP_005262880 XM_005262824 XP_005262881 XM_006714137 XP_006714200 XR_938706 XR_938707 NM_000128 NP_000119 NM_019559 |
Function | Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. |
Subcellular Location | Secreted. |
Tissue Specificity | Isoform 2 is produced by platelets and megakaryocytes but absent from other blood cells. |
Top Pathways | Complement and coagulation cascades |
Human Factor XI full length protein - ab158408 from Abcam
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Human Factor XI full length protein - ab168900 from Abcam
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Human Factor XI full length protein - ab62538 from Abcam
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Human Factor XI protein fragment - ab158409 from Abcam
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Human Factor XIa full length protein - ab62411 from Abcam
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F11 / FXI / Factor XI Blocking Peptide - LS-E1077 from LifeSpan Bioscience
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F11 / FXI / Factor XI Blocking Peptide - LS-E22325 from LifeSpan Bioscience
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Recombinant Human Coagulation Factor XI Protein - H00002160-Q01 from Novus Biologicals
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Coagulation Factor XI Recombinant Protein - H00002160-P01 from Novus Biologicals
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Coagulation Factor XI Protein - P4951 from Novus Biologicals
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F11-Antibody-Center-Blocking-peptide - BP11568c from Abgent, a WuXi AppTec company
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Recombinant Human Coagulation Factor XI, CF - 2460-SE-010 from R&D Systems
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Human F11 His tag protein - orb83317 from Biorbyt
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F11 Blocking Peptide - 33R-7950 from Fitzgerald
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Factor XI HC Blocking Peptide - abx161096 from Abbexa
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Human Coagulation Factor XI Protein - abx065983 from Abbexa
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Coagulation factor XI (F11) - H00002160-P01 from Acris Antibodies
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Coagulation factor XI (F11) - H00002160-Q01-10 from Acris Antibodies
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Coagulation factor XI (F11) - H00002160-Q01-25 from Acris Antibodies
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Coagulation factor XI (F11) - P4951 from Acris Antibodies
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F11 fusion protein - ag19065 from Proteintech Group
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F11 fusion protein - ag18004 from Proteintech Group
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Recombinant Human F11, His tagged - F11-290H from Creative Biomart
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Native Human Coagulation Factor XI - F11-2466H from Creative Biomart
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Native Human F11 - F11-26058TH from Creative Biomart
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