NANOS1

Gene Symbol	NANOS1
Entrez Gene	340719
Alt Symbol	NOS1, SPGF12
Species	Human
Gene Type	protein-coding
Description	nanos homolog 1 (Drosophila)
Other Description	EC_Rep1a|NOS-1|nanos homolog 1
Swissprots	Q8WY41
Accessions	EAW49409 Q8WY41 AF086393 AF275269 AAL36982 AF458985 AAQ04765 AI276145 BC156179 AAI56180 NM_001009553 NM_199461 NP_955631
Function	May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion. {ECO:0000269|PubMed:17047063, ECO:0000269|PubMed:18223680}.
Subcellular Location	Cytoplasm, perinuclear region. Cytoplasm. Note=Colocalizes with SNAPIN and PUM2 in the perinuclear region of germ cells.
Tissue Specificity	Testis and ovary (at protein level). Predominantly expressed in testis. Specifically expressed during germline development. In adult tissues, it is mainly expressed in spermatogonia, the stem cells of the germline. Also expressed during meiosis in spermatocytes. Not present in late, post-meiotic stage germ cells. Expressed in fetal ovaries, while it is weakly or not expressed in mature postmeiotic oocytes, suggesting that it may be expressed in premeiotic female germ cells. Expressed at high levels only in the E-cadherin deficient cell lines. Highly expressed in lung carcinomas and mostly detected in invasive tumor cells and its expression correlates with tumor aggressiveness. {ECO:0000269|PubMed:12690449, ECO:0000269|PubMed:17047063, ECO:0000269|PubMed:18223680, ECO:0000269|PubMed:19168546, ECO:0000269|PubMed:21421998}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NOS1 ELISA Kit - abx152535 from Abbexa Category ELISA Kit Sensitivity 0.053 ng/ml Range 0.156 ng/ml - 10 ng/ml

Nitric oxide synthase, brain, NOS1, Human, ELISA Kit - E0628h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 0.156-10 ng/mL

Nitric Oxide Synthase 1, Neuronal, NOS1/nNOS, Human, ELISA Kit - E-EL-H0742 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Nitric Oxide Synthase 1, Neuronal, NOS1/nNOS, Mouse, ELISA Kit - E-EL-M1281 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Nitric Oxide Synthase 1, Neuronal, NOS1/nNOS, Rat, ELISA Kit - E-EL-R1438 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Nitric Oxide Synthase 1, Neuronal, NOS1/nNOS, Rabbit, ELISA Kit - E-EL-RB0729 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Nitric Oxide Synthase 1, Neuronal, NOS1/nNOS, Chicken, ELISA Kit - E-EL-Ch1758 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Nitric Oxide Synthase 1, Neuronal, NOS1/nNOS, Porcine, ELISA Kit - E-EL-P1358 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Nitric Oxide Synthase 1, Neuronal, NOS1/nNOS, Sheep, ELISA Kit - E-EL-S0778 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Nitric Oxide Synthase 1, Neuronal, NOS1/nNOS, Guinea Pig, ELISA Kit - E-EL-GP1323 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Nitric Oxide Synthase 1, Neuronal, NOS1/nNOS, Monkey, ELISA Kit - E-EL-MK0909 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human NOS1/nNOS(Nitric Oxide Synthase 1, Neuronal) ELISA Kit - E-EL-H0742 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Human NOS1/nNOS (Nitric Oxide Synthase 1, Neuronal) CLIA Kit - E-CL-H0537 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

nanos homolog 1 (Drosophila) , ELISA Kit - MBS9335467 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Norwalk Viruses antigen (NV Ag), ELISA Kit - MBS9312368 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nos 1, ELISA Kit - MBS9311349 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nos 2, ELISA Kit - MBS9311402 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human NOS1/nNOS (Nitric Oxide Synthase 1, Neuronal) CLIA Kit - E-CL-H0537 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

NOS1/nNOS (Nitric Oxide Synthase 1, Neuronal), CLIA Kit - MBS2532683 from MyBioSource Category CLIA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/mL Range 31.25-2000pg/mL

Human NOS1 ELISA Kit - abx570102 from Abbexa Category ELISA Kit Sensitivity 0.053 ng/ml Range 0.156 ng/ml - 10 ng/ml

NOS1/nNOS - EKH1094 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Human NANOS1 ELISA Kit - E025841 from Biobool Category ELISA Kit

Human NOS1 ELISA Kit - E026616 from Biobool Category ELISA Kit Sensitivity 0.039 IU/ml

Human NOS1/nNOS ELISA Kit - E026628 from Biobool Category ELISA Kit

Human Nos 1 ELISA Kit - E026787 from Biobool Category ELISA Kit

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