C11orf30

Gene Symbol C11orf30
Entrez Gene 56946
Alt Symbol EMSY, GL002
Species Human
Gene Type protein-coding
Description chromosome 11 open reading frame 30
Other Description protein EMSY
Swissprots Q9NRH0 Q9H8I9 Q17RM7 B7ZKT8 Q8TE50 Q7Z589 Q8NBU6 Q4G109 B7ZKU2 B7ZKU0
Accessions CCQ43627 EAW74996 EAW74997 EAW74998 EAW74999 EAW75000 Q7Z589 AF226047 AAF86947 AI275430 AJ430203 CAD22881 AK023651 BAB14627 AK125114 BAG54147 AK126030 BAG54280 AK300400 BAG62131 AK304043 BAG64954 AK304106 BAG65009 AK309621 AY070433 AAL65260 BC021688 BC029375 AAH29375 BC033404 AAH33404 BC117265 AAI17266 BC143370 AAI43371 BC143374 AAI43375 BC143376 AAI43377 BG722092 BX647398 XM_005274112 XP_005274169 XM_006718637 XP_006718700 XM_006718638 XP_006718701 XM_006718639 XP_006718702 XM_011545173 XP_011543475 XM_011545174 XP_011543476 XM_011545175 XP_011543477 XM_011545176 XP_011543478 XM_011545177 XP_011543479 XM_011545178 XP_011543480 XM_011545179 XP_011543481 XM_011545180 XP_011543482 XR_949996 XR_949997 NM_001300942 NP_001287871 NM_001300943 NP_001287872 NM_001300944 NP_001287873 NM_020193 NP_064578
Function Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. {ECO:0000269|PubMed:14651845, ECO:0000269|PubMed:19131338}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14651845}. Note=Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.

EMSY (A-15) - sc-34995 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EMSY (A-15): sc-34995. Western blot analysis of EMSY expression in HeLa whole cell lysate.

EMSY (D-20) - sc-34997 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EMSY (I-14) - sc-34998 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EMSY (P-16) - sc-35000 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-EMSY antibody - ab123 from Abcam

Prices $359.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
EMSY was immunoprecipitated using 0.5mg MCF7 whole cell extract, 5µg of Rabbit polyclonal to EMSY and 50µl of protein G magnetic beads (+). No antibody was added to the control (-).The antibody was incubated under agitation with Protein G beads for 10min, MCF7 whole cell extract lysate diluted in RIPA buffer was added to each sample and incubated for a further 10min under agitation.Proteins were eluted by addition of 40µl SDS loading buffer and incubated for 10min at 70°C; 10µl of each sample was separated on a SDS PAGE gel, transferred to a nitrocellulose membrane, blocked with 5% BSA and probed with ab123.Secondary: Mouse monoclonal [SB62a] Secondary Antibody to Rabbit IgG light chain (HRP) (ab99697).Band: 141kDa; EMSY

Anti-EMSY antibody - ab4579 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Lanes 1 - 2 : Anti-EMSY antibody (ab4579) at 1 µg/mlLane 3 : Anti-EMSY antibody (ab123) at 1 µg/mlLane 1 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 2 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLane 3 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryLanes 1 - 2 : Rabbit polyclonal to Goat IgG - H&L - Pre-Adsorbed (HRP) at 1/10000 dilutionLane 3 : Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/50000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-EMSY antibody - ab87316 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab87316, at a 1/250 dilution, staining EMSY in formalin fixed, paraffin embedded human breast carcinoma sections by immunohistochemistry. detection: DAB staining.

Anti-EMSY antibody [Y474] - ab32329 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y474
Anti-EMSY antibody [Y474] (ab32329) at 1/1000 dilution + MCF7 cell lysate

Anti-C11orf30 / EMSY Antibody (aa1250-1322) - LS-C65264 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C11orf30 / EMSY Antibody (aa53-83, AP) - LS-C233251 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C11orf30 / EMSY Antibody (aa53-83, FITC) - LS-C233254 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C11orf30 / EMSY Antibody (aa53-83, APC) - LS-C233252 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C11orf30 / EMSY Antibody (aa53-83, Biotin) - LS-C233253 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C11orf30 / EMSY Antibody (aa53-83, Azide-free, HRP) - LS-C249545 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C11orf30 / EMSY Antibody (aa53-83, PE) - LS-C233256 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C11orf30 / EMSY Antibody (aa1081-1179) - LS-C306603 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-C11orf30 / EMSY Antibody (aa53-83) - LS-C319917 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-C11orf30 / EMSY Antibody - LS-C341937 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-C11orf30 / EMSY Antibody - LS-C346100 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using C11orf30 antibody. Blue: DAPI for nuclear staining.

Anti-C11orf30 / EMSY Antibody (C-Terminus, clone Y474) - LS-C49575 from LifeSpan Bioscience

Prices $480.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y474
Immunofluorescent staining of MCF-7 cells using anti-EMSY antibody.

Anti-C11orf30 / EMSY Antibody (C-Terminus) - LS-C285937 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human EMSY by Immunohistochemistry. Sample: FFPE section of human stomach adenocarcinoma Antibody: Affinity purified rabbit anti-EMSY used at a dilution of 1:250.

Anti-C11orf30 / EMSY Antibody (C-Terminus) - LS-C287165 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human EMSY by Immunohistochemistry. Sample: FFPE section of human stomach carcinoma. Antibody: Affinity purified rabbit anti-EMSY used at a dilution of 1:1000 (1Detection: DAB.

EMSY Antibody - NB100-545 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EMSY Antibody (5D1) - H00056946-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5D1

EMSY Antibody - H00056946-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
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