Gene Symbol | MECR |
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Entrez Gene | 51102 |
Alt Symbol | CGI-63, FASN2B, NRBF1 |
Species | Human |
Gene Type | protein-coding |
Description | mitochondrial trans-2-enoyl-CoA reductase |
Other Description | homolog of yeast 2-enoyl thioester reductase|mitochondrial 2-enoyl thioester reductase|nuclear receptor binding factor 1|trans-2-enoyl-CoA reductase, mitochondrial |
Swissprots | Q5SYU2 Q9BV79 Q5SYU1 Q9Y373 Q6IBU9 Q5SYU0 B3KT72 |
Accessions | EAX07653 EAX07654 EAX07655 EAX07656 Q9BV79 AF151821 AAD34058 AK025830 AK095099 BAG52984 AK225687 AK226084 AK300889 BAG62530 AK315274 AL711403 BC001419 AAH01419 CR456703 CAG32984 H17678 HY116509 JF432515 ADZ15732 XM_005245885 XP_005245942 XM_005245887 XP_005245944 XM_011541539 XP_011539841 XM_011541540 XP_011539842 XM_011541541 XP_011539843 XM_011541542 XP_011539844 XM_011541543 XP_011539845 XM_011541544 XP_011539846 XM_011541545 XP_011539847 XM_011541546 XP_011539848 XM_011541547 XP_011539849 XM_011541548 XP_011539850 XM_011541549 XP_011539851 XM_011541550 XP_011539852 XM_011541551 XP_011539853 XM_011541552 XP_011539854 XM_011541553 XP_011539855 XM_011541554 XP_011539856 XR_946662 XR_946663 XR_946664 NM_001024732 NP_001019903 NM_016011 NP_057095 |
Function | Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2- decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis. {ECO:0000269|PubMed:18479707}. |
Subcellular Location | Isoform 1: Mitochondrion {ECO:0000269|PubMed:12654921}. |
Tissue Specificity | Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung. {ECO:0000269|PubMed:12654921}. |
Top Pathways | Fatty acid elongation, Fatty acid metabolism |
Human MECR full length protein - ab99325 from Abcam
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Human MECR full length protein - ab117691 from Abcam
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MECR Antibody Blocking Peptide - LS-E22579 from LifeSpan Bioscience
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MECR Antibody Blocking Peptide - LS-E22580 from LifeSpan Bioscience
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MECR Antibody Blocking Peptide - LS-E31373 from LifeSpan Bioscience
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MECR Recombinant Protein - H00051102-P01 from Novus Biologicals
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MECR Partial Recombinant Protein - H00051102-Q01 from Novus Biologicals
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MECR Protein - NBP1-45272 from Novus Biologicals
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MECR Protein (OPPA02330) - OPPA02330 from Aviva Systems Biology
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Human MECR protein - orb90180 from Biorbyt
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MECR Blocking Peptide - 33R-1306 from Fitzgerald
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MECR protein (His tag) - 80R-1370 from Fitzgerald
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MECR (54-373, His-tag) - AR09544PU-L from Acris Antibodies
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MECR (54-373, His-tag) - AR09544PU-N from Acris Antibodies
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MECR - H00051102-Q01 from Acris Antibodies
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MECR - H00051102-Q01-10 from Acris Antibodies
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MECR - H00051102-Q01-25 from Acris Antibodies
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Mitochondrial Trans-2-Enoyl-CoA Reductase, Human Recombinant - 228-12550-1 from RayBiotech
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Recombinant Human Mitochondrial Trans-2-Enoyl-CoA Reductase - 228-12550-2 from RayBiotech
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Recombinant Human Mitochondrial Trans-2-Enoyl-CoA Reductase - 228-12550-3 from RayBiotech
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MECR, 54-373aa, Human, His tag, E.coli - 01-1866 from ARP American Research Products
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MECR Peptide - 7151P from ProSci
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MECR fusion protein - Ag6743 from Proteintech Group
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MECR fusion protein - Ag6738 from Proteintech Group
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MECR Human - ENPS-540 from NeoScientific
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