MECR

Gene Symbol MECR
Entrez Gene 51102
Alt Symbol CGI-63, FASN2B, NRBF1
Species Human
Gene Type protein-coding
Description mitochondrial trans-2-enoyl-CoA reductase
Other Description homolog of yeast 2-enoyl thioester reductase|mitochondrial 2-enoyl thioester reductase|nuclear receptor binding factor 1|trans-2-enoyl-CoA reductase, mitochondrial
Swissprots Q5SYU2 Q9BV79 Q5SYU1 Q9Y373 Q6IBU9 Q5SYU0 B3KT72
Accessions EAX07653 EAX07654 EAX07655 EAX07656 Q9BV79 AF151821 AAD34058 AK025830 AK095099 BAG52984 AK225687 AK226084 AK300889 BAG62530 AK315274 AL711403 BC001419 AAH01419 CR456703 CAG32984 H17678 HY116509 JF432515 ADZ15732 XM_005245885 XP_005245942 XM_005245887 XP_005245944 XM_011541539 XP_011539841 XM_011541540 XP_011539842 XM_011541541 XP_011539843 XM_011541542 XP_011539844 XM_011541543 XP_011539845 XM_011541544 XP_011539846 XM_011541545 XP_011539847 XM_011541546 XP_011539848 XM_011541547 XP_011539849 XM_011541548 XP_011539850 XM_011541549 XP_011539851 XM_011541550 XP_011539852 XM_011541551 XP_011539853 XM_011541552 XP_011539854 XM_011541553 XP_011539855 XM_011541554 XP_011539856 XR_946662 XR_946663 XR_946664 NM_001024732 NP_001019903 NM_016011 NP_057095
Function Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2- decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis. {ECO:0000269|PubMed:18479707}.
Subcellular Location Isoform 1: Mitochondrion {ECO:0000269|PubMed:12654921}.
Tissue Specificity Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung. {ECO:0000269|PubMed:12654921}.
Top Pathways Fatty acid elongation, Fatty acid metabolism

Mecr (G-12) - sc-160510 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Mecr (G-12): sc-160510. Western blot analysis of Mecr expression in non-transfected: sc-117752 (A) and mouse Mecr transfected: sc-125592 (B) 293T whole cell lysates and human stomach (C) and mouse heart (D) tissue extracts.

Anti-MECR antibody - ab180075 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MECR antibody (ab180075) at 1/1000 dilutionLane 1 : K562 cell line lysatesLane 2 : HeLa cell line lysatesLane 3 : HL60 cell line lysatesLane 4 : Jurkat cell line lysatesLysates/proteins at 35 µg per lane.

Anti-MECR antibody - ab68749 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-MECR antibody (ab68749) at 1/500 dilutionLane 1 : MECR transfected 293T cell lysateLane 2 : non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

Anti-MECR antibody - ab116290 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MECR antibody (ab116290) at 1 µg/ml + Human fetal brain lysate at 10 µg

Anti-MECR antibody - C-terminal - ab156268 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-MECR antibody - C-terminal (ab156268) at 1 µg/mlLane 2 : Anti-MECR antibody - C-terminal (ab156268) at 2 µg/mlLane 1 : Human brain tissue lysateLane 2 : Human brain tissue lysateLysates/proteins at 15 µg per lane.

Anti-MECR Antibody - LS-C308937 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MECR Antibody - LS-C311368 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MECR Antibody - LS-C311367 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MECR Antibody (aa167-216) - LS-C145347 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MECR antibody LS-C145347 Western blot of U937 Cell lysate. Antibody concentration 1 ug/ml.

Anti-MECR Antibody (aa289-338) - LS-C145477 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MECR antibody LS-C145477 Western blot of Fetal Brain lysate. Antibody concentration 1 ug/ml.

Anti-MECR Antibody (aa201-229) - LS-C203979 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MECR Antibody western blot of K562,HeLa,HL-60,Jurkat cell line lysates (35 ug/lane). The MECR antibody detected the MECR protein (arrow).

Anti-MECR Antibody (C-Terminus) IHC-plus™ - LS-B10065 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-MECR antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10065 concentration 10 ug/ml.

MECR Antibody - NBP1-85657 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MECR Antibody - NBP1-79910 from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MECR Antibody [NBP1-79910] - Titration: 1.0 ug/ml Positive Control: Fetal Brain.

MECR Antibody - NBP1-85659 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MECR Antibody [NBP1-85659] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

MECR Antibody - NBP1-85658 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MECR Antibody [NBP1-85658] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

MECR Antibody - H00051102-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: MECR Antibody [H00051102-B01P] - Analysis of MECR expression in transfected 293T cell line by MECR polyclonal antibody. Lane 1: MECR transfected lysate(41.03 KDa). Lane 2: Non-transfected lysate.

MECR Antibody - H00051102-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MECR Antibody [H00051102-D01P] - Analysis of MECR expression in transfected 293T cell line by MECR polyclonal antibody.Lane 1: MECR transfected lysate(40.50 KDa).Lane 2: Non-transfected lysate.

MECR Antibody - H00051102-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MECR antibody produced in rabbit - HPA022018 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MECR: <B>Cat. No. HPA022018</B>: Immunohistochemical staining of human rectum shows distinct positivity in glandular cells.

Anti-MECR antibody produced in rabbit - HPA028740 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MECR: <B>Cat. No. HPA028740</B>: Immunohistochemical staining of human breast shows strong cytoplasmic positivity in glandular cells.

Anti-MECR antibody produced in rabbit - SAB1410898 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MECR: <B>Cat. No. SAB1410898</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~40.5 kDa using MECR transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-MECR antibody produced in rabbit - HPA022030 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MECR: <B>Cat. No. HPA022030</B>: Immunohistochemical staining of human colon shows strong positivity in glandular cells.

Anti-MECR antibody produced in mouse - SAB1407442 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MECR: <B>Cat. No. SAB1407442</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~41 kDa using MECR transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

MECR antibody - C-terminal region (ARP61844_P050) - ARP61844_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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