MECR

Gene Symbol MECR
Entrez Gene 51102
Alt Symbol CGI-63, FASN2B, NRBF1
Species Human
Gene Type protein-coding
Description mitochondrial trans-2-enoyl-CoA reductase
Other Description homolog of yeast 2-enoyl thioester reductase|mitochondrial 2-enoyl thioester reductase|nuclear receptor binding factor 1|trans-2-enoyl-CoA reductase, mitochondrial
Swissprots Q5SYU2 Q9BV79 Q5SYU1 Q9Y373 Q6IBU9 Q5SYU0 B3KT72
Accessions EAX07653 EAX07654 EAX07655 EAX07656 Q9BV79 AF151821 AAD34058 AK025830 AK095099 BAG52984 AK225687 AK226084 AK300889 BAG62530 AK315274 AL711403 BC001419 AAH01419 CR456703 CAG32984 H17678 HY116509 JF432515 ADZ15732 XM_005245885 XP_005245942 XM_005245887 XP_005245944 XM_011541539 XP_011539841 XM_011541540 XP_011539842 XM_011541541 XP_011539843 XM_011541542 XP_011539844 XM_011541543 XP_011539845 XM_011541544 XP_011539846 XM_011541545 XP_011539847 XM_011541546 XP_011539848 XM_011541547 XP_011539849 XM_011541548 XP_011539850 XM_011541549 XP_011539851 XM_011541550 XP_011539852 XM_011541551 XP_011539853 XM_011541552 XP_011539854 XM_011541553 XP_011539855 XM_011541554 XP_011539856 XR_946662 XR_946663 XR_946664 NM_001024732 NP_001019903 NM_016011 NP_057095
Function Oxidoreductase with a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2- decenoyl-CoA (C10), and trans-2-hexadecenoyl-CoA (C16). May play a role in mitochondrial fatty acid synthesis. {ECO:0000269|PubMed:18479707}.
Subcellular Location Isoform 1: Mitochondrion {ECO:0000269|PubMed:12654921}.
Tissue Specificity Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung. {ECO:0000269|PubMed:12654921}.
Top Pathways Fatty acid elongation, Fatty acid metabolism

Mecr CRISPR/Cas9 KO Plasmid (h) - sc-412113 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mecr HDR Plasmid (h) - sc-412113-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mecr Double Nickase Plasmid (h) - sc-412113-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mecr Double Nickase Plasmid (h2) - sc-412113-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mecr CRISPR Activation Plasmid (h) - sc-412113-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mecr CRISPR Activation Plasmid (h2) - sc-412113-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mecr Lentiviral Activation Particles (h) - sc-412113-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mecr Lentiviral Activation Particles (h2) - sc-412113-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Mecr siRNA (h) - sc-88164 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mecr shRNA Plasmid (h) - sc-88164-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Mecr shRNA (h) Lentiviral Particles - sc-88164-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU037501 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU038841 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13156 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08440 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08440

MECR siRNA (Human) - CRH9523 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MECR (NM_016011.2) - SHH339811 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MECR(NM_001024732.1) - SHH183233 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MECR(NM_016011.2) - SHH183287 from Creative biogene

Category siRNA
Species Reactivities Human

MECR shRNA Plasmid (Human) - CHH9523 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MECR miRNA 3'UTR clone - MiUTR1H-06184 from Creative biogene

Species Reactivities Human

MECR miRNA 3'UTR clone - MiUTR1H-06185 from Creative biogene

Species Reactivities Human
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