MED8

Gene Symbol	MED8
Entrez Gene	112950
Alt Symbol	ARC32
Species	Human
Gene Type	protein-coding
Description	mediator complex subunit 8
Other Description	activator-recruited cofactor 32 kDa component|mediator of RNA polymerase II transcription subunit 8|mediator of RNA polymerase II transcription subunit MED8
Swissprots	A9IZ92 Q96FQ4 Q5JUY8 A9IZ91 Q96G25
Accessions	CCQ43950 EAX07099 Q96G25 AF521562 AAM76709 AV684532 BC010019 AAH10019 BC010543 AAH10543 BF196855 BG620658 BI488866 CB161514 CB162354 DQ891788 ABM82714 DQ896829 ABM87828 NM_001001653 NP_001001653 NM_052877 NP_443109 NM_201542 NP_963836
Function	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Location	Nucleus {ECO:0000305}.
Top Pathways	Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MED8 293T Cell Transient Overexpression Lysate(Denatured) - H00112950-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

MED8 overexpression lysate - LY404449 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MED8 overexpression lysate - LY409420 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MED8 293 Cell Lysate - 403359 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

MED8 Overexpression Lysate (Denatured) - H00112950-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

MED8 Overexpression Lysate (Native) - NBL1-12995 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MED8 Overexpression Lysate (Native) - NBP2-09082 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MED8 Overexpression Lysate (Native) - NBP2-08988 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MED8 Overexpression Lysate (Native) - NBP2-05847 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MED8 Over-expression Lysate Product - GWB-E52D0A from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human MED8 Knockdown Stable Cell Line - CSC-DC009380 from Creative biogene Category Cell Line Species Human

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