MED8

Gene Symbol	MED8
Entrez Gene	112950
Alt Symbol	ARC32
Species	Human
Gene Type	protein-coding
Description	mediator complex subunit 8
Other Description	activator-recruited cofactor 32 kDa component|mediator of RNA polymerase II transcription subunit 8|mediator of RNA polymerase II transcription subunit MED8
Swissprots	A9IZ92 Q96FQ4 Q5JUY8 A9IZ91 Q96G25
Accessions	CCQ43950 EAX07099 Q96G25 AF521562 AAM76709 AV684532 BC010019 AAH10019 BC010543 AAH10543 BF196855 BG620658 BI488866 CB161514 CB162354 DQ891788 ABM82714 DQ896829 ABM87828 NM_001001653 NP_001001653 NM_052877 NP_443109 NM_201542 NP_963836
Function	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
Subcellular Location	Nucleus {ECO:0000305}.
Top Pathways	Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Med8 (A-3) - sc-365713 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Med8 (A-5) - sc-365960 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Med8 (C-13) - sc-103619 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Med8 (FL-268) - sc-98482 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Med8 (G-14) - sc-103620 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-MED8 antibody - ab87222 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-MED8 antibody - ab112921 from Abcam Prices $370.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-MED8 antibody - ab57703 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-MED8 antibody - ab151411 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-MED8 Antibody (clone 1E5) - LS-C139470 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1E5

Anti-MED8 Antibody (aa95-122, AP) - LS-C237538 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MED8 Antibody (aa95-122, Biotin) - LS-C237540 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MED8 Antibody (aa95-122, APC) - LS-C237539 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MED8 Antibody (aa95-122, FITC) - LS-C237542 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MED8 Antibody (aa95-122, Azide-free, HRP) - LS-C248795 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MED8 Antibody (aa95-122, PE) - LS-C237543 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MED8 Antibody (aa102-130) - LS-C322945 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-MED8 Antibody (N-Terminus) - LS-C102427 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-MED8 Antibody (aa95-122) - LS-C164127 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

MED8 Antibody - NBP1-89015 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

MED8 Antibody - NBP1-89014 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

MED8 Antibody - NBP1-55435 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

MED8 Antibody (1D3) - H00112950-M01 from Novus Biologicals Prices $359.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 1D3

MED8 Antibody - NBP2-17259 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

MED8 Antibody - H00112950-B01 from Novus Biologicals Prices $349.00 Sizes 50 µl Host Mouse Clonality Polyclonal

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