Gene Symbol | IRF6 |
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Entrez Gene | 3664 |
Alt Symbol | LPS, OFC6, PIT, PPS, PPS1, VWS, VWS1 |
Species | Human |
Gene Type | protein-coding |
Description | interferon regulatory factor 6 |
Other Description | - |
Swissprots | G0ZTL0 D3DT90 B4DLE2 F5GWX8 O14896 |
Accessions | AEK31251 AEL89176 EAW93438 EAW93439 O14896 AF027292 AAB84111 AK296960 BAG59504 AK312857 BAG35709 BC014852 AAH14852 BI770148 DA016081 NM_001206696 NP_001193625 NM_006147 NP_006138 |
Function | Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:16049006, ECO:0000269|PubMed:18212048}. Note=Translocates to nucleus in response to an activating signal. {ECO:0000250}. |
Tissue Specificity | Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas. {ECO:0000269|PubMed:16049006}. |
Human IRF6 full length protein - ab132057 from Abcam
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Human IRF6 peptide - ab23204 from Abcam
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Human IRF6 protein fragment - ab114891 from Abcam
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IRF6 Antibody Blocking Peptide - LS-E25340 from LifeSpan Bioscience
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IRF6 Antibody Blocking Peptide - LS-E11479 from LifeSpan Bioscience
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IRF6 Antibody Blocking Peptide - LS-E11179 from LifeSpan Bioscience
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IRF6 Antibody Blocking Peptide - LS-E13946 from LifeSpan Bioscience
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IRF6 Antibody Blocking Peptide - LS-E13947 from LifeSpan Bioscience
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Recombinant Human IRF6 Protein - H00003664-P01 from Novus Biologicals
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Recombinant Human IRF6 Protein - H00003664-Q01 from Novus Biologicals
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IRF6 blocking peptide - GTX10925-PEP from GeneTex
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IRF6 Blocking Peptide - 33R-2986 from Fitzgerald
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Human IRF6 Protein - abx067376 from Abbexa
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IRF6 Peptide - AC21-0168-P from Abcore
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IRF6 - H00003664-P01-10 from Acris Antibodies
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IRF6 - H00003664-P01-25 from Acris Antibodies
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IRF6 - H00003664-Q01-10 from Acris Antibodies
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IRF6 - H00003664-Q01-25 from Acris Antibodies
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IRF6 Peptide - 45-781P from ProSci
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IRF6 fusion protein - ag15104 from Proteintech Group
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IRF6 fusion protein - ag3623 from Proteintech Group
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Recombinant Human IRF6 - IRF6-28727TH from Creative Biomart
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Recombinant Interferon Regulatory Factor 6 (IRF6) - RPB958Hu01 from Uscn Life Science Inc.
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Recombinant Interferon Regulatory Factor 6 (IRF6) - RPB958Mu01 from Uscn Life Science Inc.
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Recombinant Interferon Regulatory Factor 6 (IRF6) - RPB958Hu01 from Cloud-clone
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