NENF

Gene Symbol	NENF
Entrez Gene	29937
Alt Symbol	CIR2, SCIRP10, SPUF
Species	Human
Gene Type	protein-coding
Description	neudesin neurotrophic factor
Other Description	SCIRP10-related protein|Spinal cord injury related protein 10|cell growth-inhibiting protein 47|cell immortalization-related protein 2|neudesin|neuron-derived neurotrophic factor|secreted protein of unknown function
Swissprots	Q53FZ6 Q5TM90 A1KYQ8 Q9UMX5
Accessions	EAW93389 Q9UMX5 AB126219 BAD72063 AF000267 AF049672 AF173937 AAD51419 AK074431 AK223135 BAD96855 AY762102 AAX07829 BC008823 AAH08823 DB502983 DB574171 NM_013349 NP_037481 NR_026598
Function	Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190). {ECO:0000250|UniProtKB:Q9CQ45, ECO:0000269|PubMed:22748190}.
Subcellular Location	Secreted, extracellular space {ECO:0000250}.
Tissue Specificity	Ubiquitously expressed with high expression in heart. Over-expressed in various tumors including carcinomas of the uterine cervix, lymphoma, colon, lung, skin and leukemia, as well as carcinoma of the breast. {ECO:0000269|PubMed:22748190}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NENF full length protein - ab139226 from Abcam Category Protein Source E. coli Species Human

NENF / Neudesin Antibody Blocking Peptide - LS-E26463 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NENF / Neudesin Antibody Blocking Peptide - LS-E30552 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

NENF / Neudesin Antibody Blocking Peptide - LS-E24346 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Neudesin Protein - H00029937-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Neudesin Blocking Peptide - NBP1-77331PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

NENF Peptide - GTX85028-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

Neudesin/NENF blocking peptide - GTX88949-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Recombinant Human Neudesin, CF - 6714-ND-050 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Gly32-Phe172, with a C-terminal 6-His tag

Human NENF protein - orb191204 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E. coli Species Human

NENF Peptide - AC21-1301-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Neudesin - H00029937-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Neudesin - H00029937-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Neudesin Control Peptide - AP30585CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

NENF Peptide - 4753P from ProSci Category Peptide Species Human

Neudesin Peptide - 45-950P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

NENF fusion protein - Ag17683 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

NENF fusion protein - Ag8387 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human NENF, His-tagged - NENF-1263H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Neudesin Neurotrophic Factor (NENF) - RPH544Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Neudesin Neurotrophic Factor (NENF) - RPH544Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Neudesin(NENF) - CSB-YP892354HU CSB-EP892354HU CSB-BP892354HU CSB-MP892354HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Neudesin Protein, CF - 6714-ND from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Chinese Hamster Ovary cell line, CHO-derived Gly32-Phe172, with a C-terminal 6-His tag Species Human

Neudesin Neurotrophic Factor Protein (Recombinant) - abx167068 from Abbexa Category Protein Source Human Species Human

Neudesin Neurotrophic Factor Protein (Recombinant) - abx262414 from Abbexa Category Protein Species Human

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