NENF

Gene Symbol NENF
Entrez Gene 29937
Alt Symbol CIR2, SCIRP10, SPUF
Species Human
Gene Type protein-coding
Description neudesin neurotrophic factor
Other Description SCIRP10-related protein|Spinal cord injury related protein 10|cell growth-inhibiting protein 47|cell immortalization-related protein 2|neudesin|neuron-derived neurotrophic factor|secreted protein of unknown function
Swissprots Q53FZ6 Q5TM90 A1KYQ8 Q9UMX5
Accessions EAW93389 Q9UMX5 AB126219 BAD72063 AF000267 AF049672 AF173937 AAD51419 AK074431 AK223135 BAD96855 AY762102 AAX07829 BC008823 AAH08823 DB502983 DB574171 NM_013349 NP_037481 NR_026598
Function Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190). {ECO:0000250|UniProtKB:Q9CQ45, ECO:0000269|PubMed:22748190}.
Subcellular Location Secreted, extracellular space {ECO:0000250}.
Tissue Specificity Ubiquitously expressed with high expression in heart. Over-expressed in various tumors including carcinomas of the uterine cervix, lymphoma, colon, lung, skin and leukemia, as well as carcinoma of the breast. {ECO:0000269|PubMed:22748190}.

Human NENF full length protein - ab139226 from Abcam

Category Protein
Source E. coli
Species Human
14% SDS-PAGE separation of Human NENF Left: M.W. marker – 97, 66, 45, 31, 21, 14 kDa Lane 1: reduced and boiled sample, 2.55µg/lane. Lane 2: non-reduced and non-boiled sample, 2.55µg/lane.

NENF / Neudesin Antibody Blocking Peptide - LS-E26463 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NENF / Neudesin Antibody Blocking Peptide - LS-E30552 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

NENF / Neudesin Antibody Blocking Peptide - LS-E24346 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Neudesin Protein - H00029937-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Neudesin Blocking Peptide - NBP1-77331PEP from Novus Biologicals

Category Peptide
Prices $129.00
Sizes 50 µg
Species Human

NENF Peptide - GTX85028-PEP from GeneTex

Category Peptide
Prices $149.00
Sizes 50 μg
Species Human

Neudesin/NENF blocking peptide - GTX88949-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human, Mouse, Dog, Rat, Bovine

Recombinant Human Neudesin, CF - 6714-ND-050 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Gly32-Phe172, with a C-terminal 6-His tag

Human NENF protein - orb191204 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 2 μg, 10 μg
Source E. coli
Species Human

NENF Peptide - AC21-1301-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

Neudesin - H00029937-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

Neudesin - H00029937-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

Neudesin Control Peptide - AP30585CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

NENF Peptide - 4753P from ProSci

Category Peptide
Species Human

Neudesin Peptide - 45-950P from ProSci

Category Peptide
Prices $175.00
Sizes 100 µg

NENF fusion protein - Ag17683 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, T-HIS
Species Human

NENF fusion protein - Ag8387 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human NENF, His-tagged - NENF-1263H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Neudesin Neurotrophic Factor (NENF) - RPH544Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Neudesin Neurotrophic Factor (NENF) - RPH544Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Neudesin(NENF) - CSB-YP892354HU CSB-EP892354HU CSB-BP892354HU CSB-MP892354HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human Neudesin Protein, CF - 6714-ND from R&D Systems

Category Protein
Prices $329.00
Sizes 50 µg
Source Chinese Hamster Ovary cell line, CHO-derived Gly32-Phe172, with a C-terminal 6-His tag
Species Human

Neudesin Neurotrophic Factor Protein (Recombinant) - abx167068 from Abbexa

Category Protein
Source Human
Species Human

Neudesin Neurotrophic Factor Protein (Recombinant) - abx262414 from Abbexa

Category Protein
Species Human
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