NENF

Gene Symbol NENF
Entrez Gene 29937
Alt Symbol CIR2, SCIRP10, SPUF
Species Human
Gene Type protein-coding
Description neudesin neurotrophic factor
Other Description SCIRP10-related protein|Spinal cord injury related protein 10|cell growth-inhibiting protein 47|cell immortalization-related protein 2|neudesin|neuron-derived neurotrophic factor|secreted protein of unknown function
Swissprots Q53FZ6 Q5TM90 A1KYQ8 Q9UMX5
Accessions EAW93389 Q9UMX5 AB126219 BAD72063 AF000267 AF049672 AF173937 AAD51419 AK074431 AK223135 BAD96855 AY762102 AAX07829 BC008823 AAH08823 DB502983 DB574171 NM_013349 NP_037481 NR_026598
Function Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190). {ECO:0000250|UniProtKB:Q9CQ45, ECO:0000269|PubMed:22748190}.
Subcellular Location Secreted, extracellular space {ECO:0000250}.
Tissue Specificity Ubiquitously expressed with high expression in heart. Over-expressed in various tumors including carcinomas of the uterine cervix, lymphoma, colon, lung, skin and leukemia, as well as carcinoma of the breast. {ECO:0000269|PubMed:22748190}.

Neudesin CRISPR/Cas9 KO Plasmid (h) - sc-412051 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neudesin HDR Plasmid (h) - sc-412051-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neudesin Double Nickase Plasmid (h) - sc-412051-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neudesin Double Nickase Plasmid (h2) - sc-412051-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neudesin CRISPR Activation Plasmid (h) - sc-412051-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neudesin CRISPR Activation Plasmid (h2) - sc-412051-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neudesin Lentiviral Activation Particles (h) - sc-412051-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neudesin Lentiviral Activation Particles (h2) - sc-412051-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neudesin siRNA (h) - sc-88293 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neudesin shRNA Plasmid (h) - sc-88293-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neudesin shRNA (h) Lentiviral Particles - sc-88293-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU155871 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15209 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15209 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03075 from Sigma-Aldrich

Category miRNA

NENF siRNA (Human) - CRH9281 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NENF (NM_013349.4) - SHH351364 from Creative biogene

Category siRNA
Species Reactivities Human

Human NENF siRNA - orb269783 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NENF shRNA Plasmid (Human) - CHH9281 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NENF miRNA 3'UTR clone - MiUTR3H-12193 from Creative biogene

Species Reactivities Human
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