PCSK5

Gene Symbol	PCSK5
Entrez Gene	5125
Alt Symbol	PC5, PC6, PC6A, SPC6
Species	Human
Gene Type	protein-coding
Description	proprotein convertase subtilisin/kexin type 5
Other Description	prohormone convertase 5|proprotein convertase 6|protease PC6|subtilase|subtilisin/kexin-like protease PC5
Swissprots	F5H2G7 Q13527 Q92824 Q96EP4
Accessions	AFI24907 CAE75579 CAE75580 EAW62575 EAW62576 EAW62577 Q92824 AI379031 AK023096 AK056202 BAG51646 AK122718 AK225773 AK310862 AL834522 CAD39178 AM393199 CAL38077 BC012064 AAH12064 BM719207 CK023649 CN360310 DA992221 DB491139 DQ892327 ABM83253 DQ895531 ABM86457 DT932737 DV080167 DY655633 HY155058 U49114 AAA91807 U56387 AAC50643 XM_005252039 XP_005252096 XM_011518769 XP_011517071 XM_011518770 XP_011517072 XR_929806 XR_929807 NM_001190482 NP_001177411 NM_006200 NP_006191 NR_120409
Function	Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif. Plays an essential role in pregnancy establishment by proteolytic activation of a number of important factors such as BMP2, CALD1 and alpha- integrins. {ECO:0000269|PubMed:19764806, ECO:0000269|PubMed:20555025, ECO:0000269|PubMed:22740495}.
Subcellular Location	Isoform PC6A: Secreted. Note=Secreted through the regulated secretory pathway. {ECO:0000250}.
Tissue Specificity	Expressed in T-lymphocytes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PC6 full length protein - ab132450 from Abcam Category Protein Source Wheat germ Species Human

Human PC6 protein fragment - ab114944 from Abcam Category Protein Source Wheat germ Species Human

PC6 peptide - ab41413 from Abcam Category Peptide

PC6 peptide - ab41414 from Abcam Category Peptide

PC5 / PCSK5 Antibody Blocking Peptide - LS-E16016 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PC6 Protein - H00005125-P01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human PC6 Protein - H00005125-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PCSK5 blocking peptide - GTX88267-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

PCSK5 Immunizing peptide - orb15054 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

PCSK5 Blocking Peptide - 33R-1642 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PC6 Peptide - AC21-1689-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PC5 / PC6 - H00005125-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

PC5 / PC6 - H00005125-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PC5 / PC6 - H00005125-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PCSK5 Peptide - 42-223P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

PC5 fusion protein - Ag9552 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

Recombinant Human PC5, His-tagged - PC5-1546H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human PCSK5, GST-tagged - PCSK5-121H from Creative Biomart Category Protein Source wheatgerm Species Human

Recombinant Human PCSK5, His-tagged - PCSK5-122H from Creative Biomart Category Protein Source E.coli. Species Human

Recombinant Human PCSK5 - PCSK5-30549TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Proprotein Convertase Subtilisin/Kexin Type 5 (PCSK5) - RPE185Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Proprotein Convertase Subtilisin/Kexin Type 5 (PCSK5) - RPE185Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Proprotein convertase subtilisin/kexin type 5(PCSK5) ,partial - CSB-YP017644HU CSB-EP017644HU CSB-BP017644HU CSB-MP017644HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PCSK5 Protein - abx164180 from Abbexa Category Protein Species Human, Mouse, Rat

Proprotein Convertase Subtilisin/Kexin Type 5 Protein (Recombinant) - abx167011 from Abbexa Category Protein Source Human Species Human

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